Results 121 to 130 of about 486,083 (311)

Land use from water quality: development of a water quality index across Pennsylvania streams

Ecosphere, 2019
Anthropogenic stressors to lotic environments are diverse and often act in complex and synergistic ways through space and time. The need to adequately quantify and communicate these stressors in lotic environments is important for assessing stream health
Timothy A. Wertz, Matthew K. Shank
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Water Quality Index of Arkavathi River and Surrounding Groundwater

International Journal of Environmental Health Engineering
Aim: Finding out the water quality of Arkavathi river, a tributary of the Kaveri system and surrounding groundwater is the aim of the present work using the water quality index (WQI) method.
M Bharath, K Arun Kumar, Syed Ariff
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Characterization of Water Quality in Torehalla Watershed, Karnataka, India-Based on Water Quality Index [PDF]

, 2014
The quality of drinking water is a powerfulenvironmental determinant for human health. Assured drinking water is afoundation for the prevention and control of waterborne diseases. All over theworld, human population has inadequate access to potable water
Suresh, T.S., Manjunath, H.N.
core  

Effect of Water Management Technology Used in Trout Culture on Water Quality in Fish Ponds [PDF]

, 2018
Pond management requires that a specific fish culture is conducted while taking into account both production possibilities and profitability, as well as the impact it may have on the natural environment.
Ireneusz Cymes, Marcin Sidoruk
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Integrating Water Quality Index (WQI) and Multivariate Statistics for Regional Surface Water Quality Evaluation: Key Parameter Identification and Human Health Risk Assessment [PDF]

Assessing regional water quality and evaluating the associated risks to human health posed by aquatic contaminants are paramount for conserving and managing surface water resources and formulating effective local policy decisions.
Lingshuang Zhong, Yao Feng, Huajie Xia, Huabin Liu, Yu Lu, Wenjuan Zhou, Huoqian Luo, Xizhi Nong   +7 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Artificial Neural Network (ANN)-Based Water Quality Index (WQI) for Assessing Spatiotemporal Trends in Surface Water Quality—A Case Study of South African River Basins [PDF]

Artificial neural networks (ANNs) are powerful data-oriented “black-box” algorithms capable of assessing and delineating linear and multifaceted non-linear correlations between the dependent and explanatory variables.
Muthukrishnavellaisamy Kumarasamy, Talent Diotrefe Banda   +1 more
core   +1 more source