Results 131 to 140 of about 478,190 (263)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Seasonal water quality index prediction in Guilin karst water system: an explainable machine learning approach. [PDF]

Sci Rep
Dong K, Huang Y, Yang J, Li H, Lam SM, Sin JC, Wang D.   +6 more
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Multi-decadal trends and drivers of urban stream water quality in Arlington, Virginia, using the National Sanitation Foundation Water Quality Index. [PDF]

J Environ Qual
Joseph N, Maxwell RS.
europepmc   +1 more source

Improving Water Quality Index Prediction Using Regression Learning Models. [PDF]

Int J Environ Res Public Health, 2022
Mohd Zebaral Hoque J, Ab Aziz NA, Alelyani S, Mohana M, Hosain M.   +4 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Water quality index and human health risk analysis in urban drinking water sources. [PDF]

Sci Rep
Nasim I, Nawaz R, Farwa A, Ahmad S, Irshad MA, Al-Hussain SA, Irfan A, Zaki MEA.   +7 more
europepmc   +1 more source

A multivariate statistical approach and water quality index for water quality assessment for the Rokel river in Sierra Leone. [PDF]

Heliyon, 2023
Barrie A, Agodzo SK, Frazer-Williams R, Awuah E, Bessah E.   +4 more
europepmc   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Physicochemical Limnology and Water Quality Assessment of Ten Surface Water Bodies in Edo State, Nigeria

Journal of Applied Sciences and Environmental Management
The objective of this paper was to assess the physicochemical limnology and water quality assessment of ten surface water bodies in Edo State, Nigeria to determine their suitability for drinking, provide information on water quality status to the ...
G. U. Okoye, J. U. Ogbebor
doaj