Results 131 to 140 of about 489,039 (311)
Artificial Neural Network (ANN)-Based Water Quality Index (WQI) for Assessing Spatiotemporal Trends in Surface Water Quality—A Case Study of South African River Basins [PDF]
Artificial neural networks (ANNs) are powerful data-oriented “black-box” algorithms capable of assessing and delineating linear and multifaceted non-linear correlations between the dependent and explanatory variables.
Muthukrishnavellaisamy Kumarasamy +1 more
core +1 more source
PREDICTION OF WATER QUALITY USING WATER QUALITY INDEX
International Research Journal of Modernization in Engineering Technology and Science, 2023 openaire +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Methods for visualising complex water quality data [PDF]
, 2009 Includes abstract.Includes bibliographical references (leaves 157-173).The quality of South Africa’s over-stretched water resources is a matter of concern for all who depend on them for their survival and prosperity, so access to the relevant monitoring ...
Silberbauer, Michael John
core
Assessment of variability in physicochemical water parameters of Lake Nyabihoko, Western Uganda
Water ScienceThis study evaluates the spatial and seasonal variations in the physicochemical water quality parameters of Lake Nyabihoko. To assess the physicochemical quality, fifty-four (54) water samples were collected from nine sampling stations during the wet and
Abraham Atuhaire +2 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Index-Based Groundwater Quality Assessment of Nestos River Deltaic Aquifer System, Northeastern Greece [PDF]
The Nestos River delta is one of the most important and sensitive basins in Greece and Europe due to its ecosystem functions, combining intensive agricultural production with low-enthalpy geothermal energy and important ecotopes. High water quality is of
Vasiliki Kinigopoulou +6 more
core +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source