Results 131 to 140 of about 486,083 (311)
PREDICTION OF WATER QUALITY USING WATER QUALITY INDEX
International Research Journal of Modernization in Engineering Technology and Science, 2023 openaire +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
سلامت و محیط, 2021 Background and Objective: The aim of this study was to evaluate the chemical and microbial quality of bottled water in Iran and to calculate the water quality index (WQI). Materials and Methods: Different brands of bottled water (4 samples from 71 brands)
Mehrnoosh Abtahi +6 more
doaj
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Methods for visualising complex water quality data [PDF]
, 2009 Includes abstract.Includes bibliographical references (leaves 157-173).The quality of South Africa’s over-stretched water resources is a matter of concern for all who depend on them for their survival and prosperity, so access to the relevant monitoring ...
Silberbauer, Michael John
core
Assessment of variability in physicochemical water parameters of Lake Nyabihoko, Western Uganda
Water ScienceThis study evaluates the spatial and seasonal variations in the physicochemical water quality parameters of Lake Nyabihoko. To assess the physicochemical quality, fifty-four (54) water samples were collected from nine sampling stations during the wet and
Abraham Atuhaire +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Index-Based Groundwater Quality Assessment of Nestos River Deltaic Aquifer System, Northeastern Greece [PDF]
The Nestos River delta is one of the most important and sensitive basins in Greece and Europe due to its ecosystem functions, combining intensive agricultural production with low-enthalpy geothermal energy and important ecotopes. High water quality is of
Vasiliki Kinigopoulou +6 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source