Results 91 to 100 of about 486,083 (311)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Evaluation of raw water quality in Wassit governorate by Canadian water quality index
MATEC Web of Conferences, 2018 In this work an attempt has been done to evaluate the raw water quality in Wassit Governorate by using Canadian Council of Ministers of Environment Water Quality Index (CCME WAI).
Mahmood Abdulkhaleq
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Combining Water Quality Indices and Multivariate Modeling to Assess Surface Water Quality in the Northern Nile Delta, Egypt [PDF]
, 2020 Assessing surface water quality for drinking use in developing countries is important since water quality is a fundamental aspect of surface water management.
Salah Elsayed +7 more
core +1 more source
Revisión de parámetros fisicoquímicos como indicadores de calidad y contaminación del agua
Ingeniería e Investigación, 2007 Con el fin de facilitar la interpretación de los datos físicos, químicos y biológicos, cada vez más agencias medio-ambientales, universidades e institutos recurren a los indices de calidad y contaminación del agua (ICA e ICO), los cuales mediante una ...
Natalia Eugenia Samboni Ruiz +2 more
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Assessment of water quality status of Doyang River, Nagaland, India, using Water Quality Index
Applied Water Science, 2020 The Doyang River of Wokha district, Nagaland, NE India, has a strong economic and traditional attachment to the local people. It provides sufficient fertile plains and slopes for cultivation, good grounds for community fishing and hunting. It is not only
Akumtoshi Lkr, M. R. Singh, Neizo Puro
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Science Journal of University of Zakho, 2013 Consumers are reacting with water quality problems by buying bottled water which is an expensive solution and only partially resolve the problem. Subsequently, sales of bottled water have increased dramatically in the last ten years; therefore this study
Janan Jabbar Toma
doaj