An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The Volume of Water Bills in the 1999 Virginia General Assembly [PDF]
The Virginia General Assembly held its 1999 session from January 13 to February 27. During the regular session, lawmakers considered 2,735 bills and resolutions, compared to 2945 measures considered in the longer 1998 session.
Virginia Water Resources Research Center
core
WATER QUALITY INDEX – AN INSTRUMENT FOR WATER RESOURCES MANAGEMENT [PDF]
Water quality status assessment can be defined as the evaluation of physical, chemical, biological state of the water in relation with the natural state, anthropogenic effects and future uses.
PAIU MĂDĂLINA +1 more
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Groundwater Quality Assessment and Irrigation Water Quality Index Prediction Using Machine Learning Algorithms [PDF]
The evaluation of groundwater quality is crucial for irrigation purposes; however, due to financial constraints in developing countries, such evaluations suffer from insufficient sampling frequency, hindering comprehensive assessments.
Yong Jie Wong +8 more
core +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Revisión de parámetros fisicoquímicos como indicadores de calidad y contaminación del agua
Con el fin de facilitar la interpretación de los datos físicos, químicos y biológicos, cada vez más agencias medio-ambientales, universidades e institutos recurren a los indices de calidad y contaminación del agua (ICA e ICO), los cuales mediante una ...
Natalia Eugenia Samboni Ruiz +2 more
doaj
Evaluation of Irrigation Water Quality and Agricultural Suitability of Kuzgun Dam Water
The aim of this study is to evaluate the irrigation water quality of Kuzgun Dam, which supplies water to the agricultural lands of Daphan Plain, located in Erzurum Province, Türkiye. Water samples were collected from seven different locations within the
Hasan ER
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source

