Results 141 to 150 of about 425,315 (313)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Water Quality Analysis of Drinking Water Distribution Systems of Rey Township Using IWQIS Software

سلامت و محیط, 2016
Background and Objective: In this study, WQI was estimated using an Iranian software called IWQIS to assess drinking water quality in Ray Township distribution systems.
B Sepehrnia, R Nabizadeh, A.H Mahvi, S Naseri   +3 more
doaj  

Groundwater chemistry and entropy weighted water quality index of tsunami affected and ecologically sensitive coastal region of India. [PDF]

Heliyon, 2023
Krishna B, Achari VS.
europepmc   +1 more source

Ecological Water Quality Index associated with factor analysis to classify surface waters [PDF]

, 2020
Hayal Boyacıoğlu, Hülya Boyacıoğlu
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Method for screening water physicochemical parameters to calculate water quality index based on these parameters' correlation with water microbiota. [PDF]

Heliyon, 2023
Wu L, Zhang Y, Wang Z, Geng M, Chen Y, Zhang F.   +5 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Perspectives on water quality analysis emphasizing indexing, modeling, and application of artificial intelligence for comparison and trend forecasting

River
Freshwater essential for civilization faces risk from untreated effluents discharged by industries, agriculture, urban areas, and other sources. Increasing demand and abstraction of freshwater deteriorate the pollution scenario more. Hence, water quality
Rijurekha Dasgupta, Subhasish Das, Gourab Banerjee, Asis Mazumdar   +3 more
doaj   +1 more source

A multivariate statistical approach and water quality index for water quality assessment for the Rokel river in Sierra Leone. [PDF]

Heliyon, 2023
Barrie A, Agodzo SK, Frazer-Williams R, Awuah E, Bessah E.   +4 more
europepmc   +1 more source