Results 91 to 100 of about 1,201,661 (315)
The mechanical resistance of saturated stones
, 2010 This paper aims at investigating the effect of the presence of water on the mechanical resistance of stones. The presence of water, connected to the intrinsic properties of the stone (mineralogical composition, fabric, texture, etc.) and to the ...
Marini P, Bellopede R
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Ekológia (Bratislava), 2020 The soil aggregation and structure, water stability of aggregates, and peculiarities of microstructure formation of the ravine forest soils in Dnipropetrovsk region on the example of the northern variant of the ravine forest “Kapitanivskiy” have been ...
Bozhko Kateryna, Bilova Natalia
doaj +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Transferable drug resistance plasmids in fish-pathogenic bacteria
, 2000 Chemotherapeutic agents have been developed for treating bacterial infections and have been widely used for cultured fish for the last 30 years in Japan.
Aoki, Takashi
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Gypsum-cement reactive powder concrete [PDF]
Строительство уникальных зданий и сооружений, 2014 Current state of construction science causes for the repair and strengthening of unique buildings and structures using binders and concretes based on them having a high strength and speed of her set, which includes the so-called reactive powder ...
Vladimir Viktorovich Scherba
doaj
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Water struggles in Argentina: international policies, NGOs, and civil society in the pursuit of water rights [PDF]
, 2013 As the world’s most valued resource, water has been the source of debate, conflict and even wars throughout history. Its centrality to human life and dignity is universally accepted, but the best means for providing water access are highly debated.
Vietz, Maria
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Science and Engineering of Composite MaterialsThis study enhances the water resistance of mica paper/organic silicone resin composites through surface modification with 3-aminopropyltriethoxysilane (APTES).
Wang Haisheng, Ge Heyi, Xu Junke
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source