Results 91 to 100 of about 2,801,085 (309)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

A comparative study on the performance properties of breathable and non-breathable baby diaper back sheet

open access: yesTehnički Glasnik, 2018
Disposable diapers are very important in terms of babies’ health because they are in touch with the baby’s skin. Disposable diapers have sheets with different functions from each other.
Seval Uyanik, Hatice Kübra Kaynak
doaj   +1 more source

Microbial Communities of the Providence River [PDF]

open access: yes, 2015
The Providence River has been industrialized for over one-hundred years. Industries such as oil storage and metal recycling facilities have left high levels of pollutant metals, including lead (Pb), in the soil and water.
Kratch, Jacqueline
core   +1 more source

Shear resistance of rubber-ballast composites in simulated water and acid soaked conditions [PDF]

open access: yes, 2016
Ballast is one of the main structures for the railway tracks. It can resist the lateral movement under dynamic loading transferred by the passing trains with repeatedly.
Chan, Chee Ming, SM Johan, Siti Farhanah
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Apparatus facilitates high-temperature tensile testing in vacuum [PDF]

open access: yes, 1964
An apparutus for heating refractory materials to high temperatures during tensile testing includes a water-cooled stainless steel vacuum chamber. This contains a resistance heater consisting of a slit tube of tantalum or tungsten to enclose the tensile ...
Sikora, P. F.
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

An analysis of a swimmer’s passive wave resistance using experimental data and CFD simulations

open access: yes, 2014
The passive resistance of a swimmer on the free surface has previously been researched experimentally. The contribution of wave resistance to total drag for a swimmer with a velocity around 2.0 m.s-1 was found to vary from 5% for Vorontsov and Rumyantsev
Banks, J.   +3 more
core  

Privatising other people’s water: the contradictory policies of Netherlands, Norway and Sweden [PDF]

open access: yes, 2004
The Nordic countries, including Norway and Sweden, are famous for their strong welfare state and public services. Stockholm’s public sector water company hosts the world’s leading annual conference of water, in a week that celebrates its achievement of ...
Hall, David
core  

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

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