Results 81 to 90 of about 2,801,085 (309)

Exploring the differences between forward osmosis and reverse osmosis fouling [PDF]

open access: yes, 2018
A comparison of alginate fouling in forward osmosis (FO) with that in reverse osmosis (RO) was made. A key experimental finding, corroborated by membrane autopsies, was that FO is essentially more prone to fouling than RO, which is opposite to a common ...
Fane, Anthony G.   +3 more
core   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

An Overview of Grease Water Resistance

open access: yesLubricants, 2020
Many grease-lubricated components operate in wet environments, making them susceptible to water contamination which degrades their performance, functionality, and useful life. Hence, selecting a grease with appropriate water-resistant properties can have
Alan Gurt, Michael Khonsari
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

UF-pMDI Hybrid Resin for Waterproof Particleboards Manufactured at a Shortened Pressing Time

open access: yesDrvna Industrija, 2010
The aim of the study was to determine properties and potential shortening of pressing time of particleboards resinated with urea-formaldehyde (UF) resin thanks to its modification with pMDI (polymeric 4,4’ - methylene diphenyl isocyanate), introduced to ...
Dorota Dziurka, Radosław Mirski
doaj  

Taming the Floods: Using an Intellectual History of Chinese Hydraulic Thought to Address Contemporary Issues in China’s Water Governance [PDF]

open access: yes, 2018
China’s current hydraulic systems are in a state of atrophy, caused by sustained damage over centuries to infrastructure that has changed very little. Added to an already weak infrastructure is a relatively new crisis of water scarcity, which is forcing ...
Danison, Sophia Rose
core   +1 more source

Carbon dioxide exchange in lichens: Relationship between the diffusive resistance of carbon dioxide and water vapour [PDF]

open access: yes, 1982
Gaseous diffusion resistances for carbon dioxide and water vapour, thallus water content and thallus water potential were experimentally determined on species of the Stictaceae.
Green, T.G. Allan, Snelgar, W.P.
core   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Adobe-bricks surface treatment methods for improved water resistance [PDF]

open access: yesConstructii: Journal of Civil Engineering Research, 2018
The main problem with clay-based surfaces is the reduced resistance to water action. Literature does not indicate scientifically validated solutions for surface treatment.
Gabriela CĂLĂTAN   +3 more
doaj  

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