Results 71 to 80 of about 12,262,922 (372)
Integrated Water Resources Management Approaches to Improve Water Resources Governance
Water, 2020 The water crisis can alternatively be called a governance crisis. Thus, the demand for good water governance to ensure effective water resources management and to attain specific water goals is growing.
J. Katusiime, B. Schütt
semanticscholar +1 more source
A Transdisciplinary Review of Deep Learning Research and Its Relevance for Water Resources Scientists [PDF]
Water Resources Research, 2017 Deep learning (DL), a new generation of artificial neural network research, has transformed industries, daily lives, and various scientific disciplines in recent years. DL represents significant progress in the ability of neural networks to automatically
Chaopeng Shen
semanticscholar +1 more source
Minimal-time bioremediation of natural water resources [PDF]
, 2011 We study minimal time strategies for the treatment of pollution of large volumes, such as lakes or natural reservoirs, with the help of an autonomous bioreactor. The control consists in feeding the bioreactor from the resource, the clean output returning
Cabrera, Hector Ramirez +3 more
core +6 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Scientific ReportsEvapotranspiration (ET) is a critical component of the water and energy cycles in desert grassland ecosystems. However, modeling ET in arid grasslands faces significant challenges due to data scarcity, high spatiotemporal heterogeneity, and complex ...
Haitao Chen +4 more
doaj +1 more source
Water Demand Forecast in the Baiyangdian Basin with the Extensive and Low-Carbon Economic Modes
Journal of Applied Mathematics, 2014 The extensive and low-carbon economic modes were constructed on the basis of population, urbanization level, economic growth rate, industrial structure, industrial scale, and ecoenvironmental water requirement.
T. L. Qin, D. H. Yan, G. Wang, J. Yin
doaj +1 more source
Water, 2020 Agriculture is the most important sector with regard to water resources management due to its social, economic, hydrological, and environmental aspects, and many scholars and researchers have been driven to investigate the dynamic interrelationships ...
Ahmed F. Mashaly, A. Fernald
semanticscholar +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Applied Water Science, 2020 This paper quantified the level of heavy metals contamination, identified possible sources of pollution, and assessed the human health risks associated with drinking water resources in Ojoto Province, Nigeria. The study’s gross findings revealed that the
J. C. Egbueri, C. Mgbenu
semanticscholar +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source