Results 81 to 90 of about 951,237 (293)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
The effects of graded levels of calorie restriction : I. impact of short term calorie and protein restriction on body composition in the C57BL/6 mouse [PDF]
, 2015 We acknowledge the BSU staff for their invaluable help with caring for the animals and anonymous referees for their inputs. The work was supported by the Biotechnology and Biological Sciences Research Council (BBSRC) of the UK (Standard grant BB/G009953 ...
Aspden, Richard M +16 more
core +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Increasing Income and Employment through Sustainable Farming Systems in Water Scarce Region of Uttar Pradesh [PDF]
The farming systems in the water-scarce region of semiarid Uttar Pradesh have been examined. The availability of land and also of water has become the most limiting factors in farming for increasing the levels of farm income and employment. Therefore, an
Jain, D.K. +2 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Proposing a strategy based on body-thermal status to improve the welfare of heat-stressed and water-deprived goats () [PDF]
Animal BioscienceObjective Despite the considerable body of research on the effects of heat stress coupled with water scarcity (either through restriction or deprivation) on goats, aimed at enhancing their welfare, there remains a notable gap in the literature regarding ...
Emad M. Samara +3 more
doaj +1 more source
Floresta e Ambiente, 2020 Catingueira (Poincianella pyramidalis Tul. L. P. Queiroz) is an endemic species of the Caatinga, with great economic potential. Research on the development of this species under conditions of water restriction, common in the Northeastern semi-arid region,
Moadir de Sousa Leite +5 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Ciência e Agrotecnologia, 2003 Acremonium strictum é patogênico ao milho e a outras culturas, podendo causar podridão de sementes, podridão de colmos e a morte de plântulas. Trata-se de um fungo que pode interferir no vigor, estande e produtividade final das plantas.
Hudson Teixeira, José da Cruz Machado
doaj +1 more source