Results 81 to 90 of about 1,114,301 (300)

Enhanced NSGA-II algorithm based on novel hybrid crossover operator to optimise water supply and ecology of Fenhe reservoir operation

Scientific Reports
Reservoir-operation optimisation is a crucial aspect of water-resource development and sustainable water process management. This study addresses bi-objective optimisation problems by proposing a novel crossover evolution operator, known as the hybrid ...
Qinglai Xiong, Ling Dong, Hu Chen, Xueping Zhu, Xuehua Zhao, Xuerui Gao   +5 more
doaj   +1 more source

Wetlands for Water Quality Management – The Science and Technology

, 2011
Wetlands are defined as water systems with marsh or fen and with water that is static or flowing, fresh or brackish, the depth of which at low tide is below 6m [5]. Natural wetlands are characterized by emergent aquatic vegetation such as cattails (typha), rushes (Scirpus) and reeds (Phragmites), and by submerged and floating plant species.
Vikas Rai, A. M., Rana D., R. K., Suman Bhowmick   +4 more
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Science and Technology to Ensure the Safety of the Nation’s Drinking Water

, 2016
Despite the weaknesses of damaged or outdated infrastructure, new advances in science and technology can be utilized to develop safe and reliable methods for monitoring and treating water systems to ensure clean drinking water.
PCAST Science and Technology to Ensure the Safety of the Nation's Drinking Water - Working Group, Cassel, Christine, Bierbaum, Rosina   +2 more
core  

Potable water reuse through advanced membrane technology [PDF]

, 2018
Recycling water from municipal wastewater offers a reliable and sustainable solution to cities and regions facing short-age of water supply. Places including California and Singapore have developed advanced water reuse programs as an integral part of ...
Tang, CY, Long D. Nghiem, Hao Guo, Tang, C, Yang, Zhe, Yang, Z, Nghiem, Long D, Wen, JJ, Nghiem, LD, Zhe Yang, Guo, Hao, Cornelissen, E, Guo, H, Chuyang Y. Tang, Jason J. Wen, Emile Cornelissen, Tang, Chuyang Y, Wen, Jason J, Cornelissen, Emile   +18 more
core   +1 more source

Water Science and Technology Board annual report, 1987 [PDF]

, 1988
In 1982, the National Research Council chose to recognize the importance of water resource issues by establishing the Water Science and Technology Board (WSTB). During the five years since its first meeting in November 1982, the WSTB has grown and matured. The WSTB has met 14 times to provide guidance and plan activities.
openaire   +4 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Sustainable water : RSC (Issues in environmental science and technology)

, 2010
It is predicted that climate change will result in big changes to the global distribution of rainfall, causing drought and desertification in some regions and floods in others.

core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source