Results 101 to 110 of about 1,114,301 (300)

Pakistan’s Water Economy : Running Dry

, 2008
With an average rainfall of under 240 milli-meters a year, Pakistan is one of the world's most arid countries. The population and the economy are heavily dependent on an annual influx of water into the ...
Briscoe, John, Qamar, Usman
core   +1 more source

A novel hybrid model by integrating TCN with TVFEMD and permutation entropy for monthly non-stationary runoff prediction

Scientific Reports
Accurate prediction of runoff is of great significance for rational planning and management of regional water resources. However, runoff presents non-stationary characteristics that make it impossible for a single model to fully capture its intrinsic ...
Huifang Wang, Xuehua Zhao, Qiucen Guo, Xixi Wu   +3 more
doaj   +1 more source

Science and Technology for Water Purification: Achievements and Strategies

Water
Water scarcity and pollution remain two of the most pressing global challenges, with profound implications for public health, environmental sustainability, and economic development [...]
Yuanfeng Qi, Kai He
openaire   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Evaluation Of White Water Reuse In The Bleaching Process For Reducing Fresh Water Consumption

, 2015
The main objective of this work is to study the technical viability of using the effluent generated in paper machines (white water) in the wash presses of the bleaching stage, reducing fresh water consumption.
d'Angelo J.V.H., Andrade A.A., Gloria P.M., Perissotto D.O., Lima R.A.   +4 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Hydrogeochemical characteristics and spatial distribution of groundwater quality in Arusha well fields, Northern Tanzania

Applied Water Science, 2018
Arusha aquifers have been exploited intensively serving as the main source of domestic water supply in the city. But the quality of groundwater is not clearly documented for future planning and management.
Nyamboge Chacha, Karoli N. Njau, George V. Lugomela, Alfred N. N. Muzuka   +3 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Multi-functional 3D honeycomb ceramic plate for clean water production by heterogeneous photo-Fenton reaction and solar-driven water evaporation

, 2019
The application of solar-driven water evaporation process in clean water production via solar distillation is recently intensively investigated. The phase change and mass transfer processes during the solar-driven water evaporation process can directly ...
Aldrees, Yara, Aleid, Sara, Wang, Peng, Shi, Yusuf, Shi, Le, Zhang, Chenlin, Zhuo, Sifei   +6 more
core   +1 more source