Results 101 to 110 of about 710,433 (307)
Anesthetic-sensitive ion channel modulation is associated with a molar water solubility cut-off
BMC Pharmacology and Toxicology, 2018 Background NMDA receptor modulation by hydrocarbons is associated with a molar water solubility cut-off. Low-affinity phenolic modulation of GABAA receptors is also associated with a cut-off, but at much lower molar solubility values.
Robert J. Brosnan, Trung L. Pham
doaj +1 more source
, 1986 Brings together the diverse experience of those working with and using water-soluble polymers. Gives a detailed description of important advances in inversion emulsion polymerization of synthetic water-soluble monomers.Reports on the tremendous increase in research and the state-of-the-art in fundamental concepts and application performance of water ...
openaire +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
A Natural Flavour in an Amphiphilic Association Structure [PDF]
, 1995 The miscibility ofa banana flavour, amyl acetate, in a water-in-oil microemulsion of water/sodium dodecyl sulphate (SDS): hexan-1-01 (35:65) in n-decane and fJ-xylene system was carried out at 30°e.
Ahmad, Faujan +2 more
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Octanol/Water Partitioning Coefficients of PCB Mixtures for Environmental Fate and Transport [PDF]
, 2013 Polychlorinated biphenyls (PCBs) are a human and environmental toxin introduced to the environment from the 1920’s to the 1970’s from manufacturing items such as transformers and capacitors.
Cicilio, Phylicia
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
LIQUID INSULATING MATERIALS MOISTURE CONTENT CONTROL METHODS. CONDITION AND PROBLEMS
Известия высших учебных заведений: Проблемы энергетики, 2018 The article is dedicated to the issue of water influence on the main insulation of high voltage equipment and its technical condition in general.
S. M. Korobeynikov, M. N. Lyutikova
doaj +1 more source
INFLUENCE OF LINEAR ALKYLBENZENE SULFONATE (LAS) AS ORGANIC COSOLVENT ON LEACHING BEHAVIOR OF PCDD/FS FROM FLY-ASH AND SOIL [PDF]
, 1995 The leaching of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) was measured in soil and standard fly ash column eluted with pure water and linear alkylbenzene sulfonate (LAS)- water. The data obtained were used to evaluate the leachability
B. Henkelmann +6 more
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source