Results 231 to 240 of about 7,522,269 (313)

Is prodrug design an approach to increase water solubility?

International journal of pharmaceutics, 2019
Water solubility has been identified as a critical parameter and the main responsible by affecting poor performance of oral drug delivery. Poorly soluble drugs can originate unsatisfactory ADME properties leading to low oral bioavailability, insufficient
B. M. A. Sanches, E. Ferreira
semanticscholar   +1 more source

Nanoencapsulation by electrospinning to improve stability and water solubility of carotenoids extracted from tomato peels.

Food Chemistry, 2018
The current study demonstrated the electrospinning technique to stabilize the carotenoids. Gelatin nanofibers containing the carotenoids extracted from tomato peel (TP) were successfully fabricated with above 90% encapsulation efficiency by ...
Tuğba İnanç Horuz, K. B. Belibagli
semanticscholar   +1 more source

Water-soluble ionic benzoporphyrins

Chemical Communications, 2012
Novel ionic water-soluble tetrabenzoporphyrins have been successfully synthesized via a cascade reaction based on the Heck reaction. The UV-Vis spectra of these porphyrins displayed red-shifted and broadened Soret bands, and significantly enhanced Q bands. These porphyrins are highly water soluble.
Lin, Jiang, Ross A, Zaenglein, James T, Engle, Chris, Mittal, C Scott, Hartley, Christopher J, Ziegler, Hong, Wang   +6 more
openaire   +2 more sources

Water-soluble stilbene dendrimers

Chemical Communications, 2002
The third generation of novel photo-responsive water-soluble stilbene dendrimer (trans- and cis-G3 WSD) undergoes unusual one-way trans-to-cis isomerization to give 100% of cis isomer at the photostationary state on UV irradiation in water.
Junpei, Hayakawa, Atsuya, Momotake, Tatsuo, Arai   +2 more
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Water Solubility of Cholesterol

Journal of Pharmaceutical Sciences, 1965
Four different procedures showed the solubility of cholesterol in water at 30.0° to be: 2.6 × 10 −8 , 2.6 × 10 −8 , 2.7–2.9 × 10 −8 , and 2.5 × 10 −8 Gm./ml.
H Y, Saad, W I, Higuchi
openaire   +2 more sources

Water‐soluble chiral metallopeptoids

Peptide Science, 2015
ABSTRACTMetal ions play a significant role in the activity of biological systems including catalysis, recognition and folding. Therefore, introducing metal ions into peptidomimetic oligomers is a potential way for creating biomimetic metal complexes toward applications in sensing, recognition, drug design and catalysis.
Maria, Baskin, Galia, Maayan
openaire   +2 more sources

Eutectic mixtures as an approach to enhance solubility, dissolution rate and oral bioavailability of poorly water-soluble drugs.

International journal of pharmaceutics, 2020
Eutectic mixtures have been known for a long time in the pharmaceutical field. However, its potential as a system to improve the solubility and dissolution of poorly water-soluble drugs remains little explored.
Giovana Carolina Bazzo, Bianca Ramos Pezzini, Hellen Karine Stulzer   +2 more
semanticscholar   +1 more source

Water-Soluble BODIPY Derivatives

Organic Letters, 2009
New, water-soluble BODIPY dyes have been readily obtained from various BODIPY cores by reactions involving the introduction of novel sulfonated peptide chains by either coupling or substitution to give dimethylpropargylamine derivatives subsequently quaternized by reaction with propanesultone.
Song Lin, Niu, Gilles, Ulrich, Raymond, Ziessel, Agneta, Kiss, Pierre-Yves, Renard, Anthony, Romieu   +5 more
openaire   +2 more sources

Water‐Soluble Metallocene‐Containing Polymers

Macromolecular Rapid Communications, 2016
Metallocenes are organometallic compounds with reversible redox profiles and tunable oxidation and reduction potentials, depending on the metal and substituents at the cyclopentadienyl rings. Metallocenes have been introduced in macromolecules to combine the redox‐activity with polymer properties.
Alkan, A., Wurm, F.
openaire   +3 more sources

ABSORPTION OF WATER-SOLUBLE VITAMINS

British Medical Bulletin, 1967
An account of the absorption of water-soluble vitamins must deal with the intestinal transport of a group of structurally unrelated compounds with widely different properties. The characteristics of absorption of several members of the group have not yet been adequately investigated. It is therefore difficult to make many valid generalizations.
openaire   +3 more sources