Results 71 to 80 of about 1,083,484 (267)
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Irrigation of young grapefruits with desalinated seawater: Agronomic and economic outcomes
Agricultural Water ManagementGiven the current scarcity of freshwater resources, it is imperative to explore new agricultural management options to sustainably enhance food production. Desalinated seawater (DSW) presents a promising solution for irrigation in water-stressed regions.
Alberto Imbernón-Mulero +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Preharvest Water Stress for Valley Sugar Beets
California Agriculture, 1965 Moderate water stress prior to sugar beet harvest did not significantly reduce sugar production in Kern County tests. Higher sugar content of roots and lower production costs could make this practice profitable, if stress is not prolonged.
G Ferry, F Hills, R Loomis
doaj
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Phytopathology ResearchBacterial adaptation in complex environments is contingent upon the rapid perception of stress through sensory and regulatory domains, which subsequently activate a diverse array of signaling factors. Many Phytobacteria rely on Extracytoplasmic Function (
Muhammad Asif +5 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
, 2013 Climate changes and water availability cause an important impact in agriculture, food disposal and consequently in human health. According to the U.S. Census Bureau, the total population of the World is now over 7,032 billion, and all growth projections for developed and undeveloped countries show that a total of 9 million of inhabitants will be ...
Sonia Marli +4 more
openaire +2 more sources
AgronomyPhosphorus (P) is a vital element for optimal crop growth and agricultural productivity. Struvite, a P precipitate obtained from wastewater, is recognized as a slow-release, low-solubility fertilizer.
Valentina Carrillo +7 more
doaj +1 more source