Results 51 to 60 of about 1,083,484 (267)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Root exudate–assisted phytoremediation of copper and lead contamination using Rumex acetosa L. and Rumex K-1

Ecotoxicology and Environmental Safety
Heavy metal pollutants can be effectively removed from soil through phytoremediation using root exudates. Herein, experiments were conducted to assess the phytoremediation capabilities of Rumex acetosa L.
Mengfan He, Huizhen Yin, Zhuoliang Liu, Fan Luo, Xining Zhao, Huike Li, Xiaolin Song   +6 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

When the taps run dry: Water stress and social unrest revisited

Revista UNISCI, 2018
Water stress presents a wide range of concerns that can jeopardize international security. Neo-Malthusians scholars constantly warn of water conflicts, while institutionalists argue that possible water conflicts are the result of poor water distribution ...
Alfonso Sánchez, Guillermo Rylance
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Past, present and future of Indian sandalwood (Santalum album) cultivation and commercial prospects

Discover Applied Sciences
The sandalwood (Santalum album) tree holds significant commercial and cultural value globally, particularly in India. Among the 17 species within the Santalum genus, Santalum album stands out due to its high oil content and the presence of favorable ...
S. B. Chavan, A. R. Uthappa, A. R. Chichaghare, S. Suresh Ramanan, Raj Kumar, A. Keerthika, A. Arunachalam, Ramakrishna Hegde, Dinesh Jinger, Vijay Singh Meena, Manish Kumar, C. B. Harisha, V. D. Kakade, A. S. Morade, G. B. Rawale, Rupali Singh, K. Sammi Reddy   +16 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Interpretable across-period ensemble learning with multi-stress dataset fusion to enhance early-stage yield prediction under combined water and nitrogen stress using hyperspectral sensing

Agricultural Water Management
Machine learning models fitted with remote sensing data facilitate accessible and timely crop yield prediction. Since crop canopy structure influences dry matter accumulation and signals physiological status, the predictive accuracy of dependent models ...
Bohan Mao, Xiaoxiao Sun, Hao Li, Feng Wu, Xiaohui Kuang, Ying Feng, Wanna Fu, Weiguang Zhai, Yafeng Li, Fuyi Duan, Qian Cheng, Xiuqiao Huang, Zhen Chen   +12 more
doaj   +1 more source