Results 121 to 130 of about 975,542 (309)

The Influence of High Operation Platform Mode on U-Shaped Automated Container Terminal Efficiency

open access: yesIEEE Access
Improving operational efficiency and reducing energy consumption are common objectives for all ports. In previous research by authors, a new high operation platform mode was proposed.
Xiao-Jun Li   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Sediment water column nutrient exchanges in southern Chesapeake Bay nearshore environments

open access: yes, 1993
Using field and modeling methodology, the effects of benthic microcommunities and physical transport mechanisms on sediment nutrient flux were investigated for two nearshore sediment types on Virginia's Eastern Shore.
Gallagher, Daniel L.   +2 more
core  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

REVIEW OF MODELING OF WATER FLOW AND SOLUTE TRANSPORT IN THE VADOSE ZONE: Stochastic Approaches

open access: yes, 1994
Hydrologic properties of the vadose zone are heterogeneous at many different scales. An accurate prediction of water flow and solute transport in the vadose zone requires detailed information about spatial distributions of the properties. Collecting such
Yeh, T.-C. Jim, McCord, J. T.
core  

Research on the Construction of a Digital Twin System for the Long-Term Service Monitoring of Port Terminals

open access: yesJournal of Marine Science and Engineering
Structural damage is a prevalent issue in long-term operations of harbor terminals. Addressing the lack of transparency in terminal infrastructure components, the limited integration of sensor monitoring data, and the insufficient support for feedback on
Jinqiang Bi   +4 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Nanoscale Fluid Transport: From Molecular Signatures to Applications

open access: yes, 2015
Motivated by the fact that many novel fluid transport phenomena have been discovered at nano length scales, in this thesis I use molecular dynamics simulations to investigate how a solid surface affects the fluid properties and fluid transport in ...
Ho, TA
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Artificial Intelligence in Ship Trajectory Prediction

open access: yesJournal of Marine Science and Engineering
Maritime traffic is increasing more and more, creating more complex navigation environments for ships. Ship trajectory prediction based on historical AIS data is a vital method of reducing navigation risks and enhancing the efficiency of maritime traffic
Jinqiang Bi   +4 more
doaj   +1 more source

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