Results 111 to 120 of about 975,542 (309)
Root developmental responses to heterogeneous water and nitrogen supply [PDF]
, 2012 Better understanding of the interaction between the soil physical properties determining water and nitrate availability and the root proliferation and gene expression components of nutrient acquisition could contribute to food security, but may have been
Chapman, N., CHAPMAN, NICHOLAS
core
Combined Effect of Tides and Wind on Water Exchange in a Semi-Enclosed Shallow Sea
, 2019 The Bohai Sea is a semi-enclosed shallow sea in China, where the tides and wind are the dominant factors contributing to the water exchange with the Yellow Sea.
Jian Sun +7 more
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Management of water transport on the Odra river in the historical aspect
, 2008 The publication contains the retrospection of management and the development of water transport on the Odra river in the historical aspect. In fact, XVII century is the beginning of constructing frames of homogenous river-shipping administration on the ...
Zamiar, Zenon; the International University of Logistics and Transport in Wrocław
core
Comparisons of Machine Learning Methods in Ship Speed Prediction Based on Shipboard Observation
Journal of Marine Science and EngineeringThis study presents a novel approach to predicting ship speed based on real-time voyage observation data, aiming to enhance maritime safety and operational efficiency.
Weidong Gan, Dianguang Ma, Yu Duan
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Transport of Emergency Drinking Water Supplies to Population
, 2012 The importance of emergency supply of drinking water with the emphasis on its transport. Transport of drinking water to the population affected by emergency event and state of crisis using various transport alternatives for supply.Organization and ...
Jakubčeková, Júlia; University of Žilina +1 more
core