Results 101 to 110 of about 975,542 (309)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
The Mechanism of Isotonic Water Transport [PDF]
The Journal of General Physiology, 1964 The mechanism by which active solute transport causes water transport in isotonic proportions across epithelial membranes has been investigated. The principle of the experiments was to measure the osmolarity of the transported fluid when the osmolarity of the bathing solution was varied over an eightfold range by varying the NaCl concentration or by ...
openaire +2 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Direct numerical simulation of turbulent scalar transport across a flat surface [PDF]
, 2014 To elucidate the physical mechanisms that play a role in the interfacial transfer of atmospheric gases into water, a series of direct numerical simulations of mass transfer across the air-water interface driven by isotropic turbulence diffusing from ...
Herlina, H +3 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Washington Water Resource: v.11:no.3(2000:summer)
, 2000 Articles include: Technology Review: Ultra-Urban Stormwater Treatment Technologies; A Survey of Ditches Along County Roads for their Potential to Affect Stormwater Runoff Water Quality; Fate and Transport of Nonpoint Source Metals: Design of Highway ...
Center for Urban Water Resources Management
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Coal Gasification in Southeastern Ohio : Water Supply and Demand [PDF]
, 1975 This study was supported in part by the Office of Water Research and Technology, U.S. Department of the Interior under Project A-041-OHIO(print) iii, 77 p.
Whitlatch, Elbert E. (Elbert Earl), 1942-
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Challenges in water and wastewater transport systems in cold regions
, 2016 The water and wastewater transport systems faces severe challenges due to climate change, resource constrain and an aging infrastructure. In cold regions the challenges are also related to general conditions societies have in common, e.g.
Hedström, Annelie +2 more
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