Results 91 to 100 of about 975,542 (309)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Humic Acid Transport in Water-Saturated Porous Media

, 2010
The presence of humic acid (HA) in water poses environmental problems because it enhances the transport of several contaminants. A series of column experiments was conducted toward studying HA transport in different porous media under various pH, ionic ...
Horton Robert, Shao, MG, Shao Mingan, Wei Xiaorong   +3 more
core  

Assessment of risks of occurrence and consequences of oil spill in the area of the Cheboksary river port

RUDN Journal of Ecology and Life Safety, 2019
Due to the significant number of oil spill incidents, spill forecasting plays an important role in developing plans for their prevention and response. In this article, the authors propose an analysis of the risk of oil pollution from ships in the region ...
Andrey E. Plastinin, Olga L. Domnina, Vasily N. Zakharov, Ayrat M. Safarov   +3 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Functional magnetic resonance microscopy of long- and short-distance water transport in trees

, 2009
Due to their long life span, changing climatic conditions are of particular importance for trees. Climate changes will affect the water balance, which can become an important limiting factor for photosynthesis and growth. Long-distance water transport in
Homan, N.
core  

Mathematical Model of Heavy Metal Transfer and Transport in Lake Erie [PDF]

, 1979
This study was supported in part by the Office of Water Resources Technology, U.S. Department of Interior under project A-045-OHIO(print) vii, 141 p. : ill. ; 27 cm.Numerical integration of mathematical functions representing the concentration of mercury,
Walters, Lester J., Jr., Drain, David C.
core  

Experimental investigation into the influence of calcium aluminate cement on the micro- and macro-mechanical properties of the interfacial transition zone in geopolymer concrete

Developments in the Built Environment
This study aimed to analyze the properties of the interfacial transition zone (ITZ) in fly ash geopolymer concrete (FAGC) containing various concentrations of calcium aluminate cement (CAC) (5%, 10%, 15%, and 20%).
Yamin Wang, Hongbiao Liu, Zhichao Nie, Runze Xue, Wei Zhu, Xiping Sun   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Predicting water transport in multilayer coatings [PDF]

, 2012
Water transport in polymer coatings is a key process in their failure. Mostly, such systems are composed of multiple layers to meet the required specifications.
Huinink, H.P., Ven, L.G.J. van der, Erich, SJF Sebastiaan, Adan, O.C.G., Erich, S.J.F., Baukh, V Viktor, Baukh, V., Huinink, H.P.; id_orcid, Huinink, HP Henk, Adan, O.C.G.; id_orcid, Ven, LGJ Leendert van der, Adan, OCG Olaf, Ven, van der, L.G.J.   +12 more
core   +1 more source