Results 101 to 110 of about 3,375,307 (312)

Catchment management in semi-arid area of central South Africa: Strategy for improving water productivity

, 2006
Published ArticleIn the semi-arid part of central South Africa, population growth and industrial development are the driving forces for an increased demand for water. This accentuates the need for wise decisions by catchment management agencies (CMAs),
WOYESSA, YE, LD Van Rensburg, Hensley, M
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Water Footprint Accounting Along the Wheat-Bread Value Chain: Implications for Sustainable and Productive Water Use Benchmarks

, 2018
Efficient and wise management of freshwater resources in South Africa has become critical because of the alarming freshwater scarceness. The situation requires a thorough examination of how water is utilized across various departments that use water ...
Pascalina Matohlang Mohlotsane, Enoch Owusu-Sekyere, Leon Daniel Van Rensburg, Henry Jordaan, Jonannes Hendrikus Barnard   +4 more
core   +1 more source

Defining Sustainability in an Input–Output Model: An Application to Spanish Water Use

, 2020
The continuous increase in freshwater consumption threatens water availability worldwide, especially in dry and arid regions. In this paper, we evaluate the sustainability of water use in Spain, a Mediterranean country that suffers from a permanent ...
Ángeles Cámara, Maria Llop
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Research in water resources for Idaho

, 1963
Summary of the goals, priorities and mission of the University of Idaho's Policy and Coordinating Committee on Water Resources and the Water Resources Committee. Summary of ongoing research. Lists priority of needs for future work.
University of Idaho, Water Resources Committee
core  

A Systematic Review on Drivers of Water-Use Behaviour among Agricultural Water Users

Sustainable Development Goal 6 (SDG 6) is closely linked to the sustainable management of water resources and sanitation worldwide. SDG 6.4, in particular, aims to significantly improve water-use efficiency across all sectors by 2030.
Yonas T. Bahta, Markus A. Monteiro, Henry Jordaan   +2 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Monitoring long-term peat subsidence with subsidence platens in Zegveld, The Netherlands

Geoderma
Peat oxidation in peat meadow areas is causing greenhouse gas emissions as well as land subsidence. Due to yearly fluctuations in soil surface level, long-term monitoring is needed to determine long-term net subsidence rates.
Harry T.L. Massop, Rudi Hessel, Jan J.H. van den Akker, Sanneke van Asselen, Gilles Erkens, Paul A. Gerritsen, Frank H.G.A. Gerritsen   +6 more
doaj   +1 more source

Evaluation of the wind erosion risks in GIS

Soil and Water Research, 2007
The paper refers to the possibilities of the evaluation of the wind erosion risks by using a model created in GIS. The model exploits the pedological information database for determining the potential risks of soils by wind erosion.
Jana Podhrázská, Ivan Novotný
doaj   +1 more source