Results 111 to 120 of about 3,375,307 (312)

Improving agricultural water use efficiency in and semiarid areas of China

, 2006
Water shortage in China, particularly in the north and northwest of China, is very serious. The region accounts for half of the total area of China, but has less than 20% of total national available water resources.
Deng XP, Shan L, Zhang HP, Deng, XP
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Design and Implementation of Low-Cost Redundant Subsystems for PFAL Reliability

Agriculture
The increasing adoption of Plant Factories with Artificial Lighting (PFAL) has intensified the reliance on Internet of Things (IoT) technologies for real-time monitoring and control of environmental and operational variables.
Gracia Muñoz Jaimes, Mauricio Samano Solano, Luis Arturo Soriano   +2 more
doaj   +1 more source

Impact of China’s Urbanization on Water Use and Energy Consumption: An Econometric Method and Spatiotemporal Analysis

, 2018
As important subsystems of the urban environment, water resources and energy are necessary for normal urban functions and play an important supporting role in urbanization. The rapid development of China’s economy is increasingly dependent on these
Xuelei Zhang, Xinyi Song, Jianhua Wang, Yong Zhao, Baodeng Hou, Yan Wang, Yicheng Wang, Weihua Xiao   +7 more
core   +1 more source

A Review of Modeled Water Use Efficiency of Highly Productive Perennial Grasses Useful for Bioenergy

, 2020
Whole plant productivity is obviously the ultimate product of leaf photosynthesis and this has led to numerous efforts to relate the two. However, often with perennial grasses, plant productivity is more sink-limited than source-limited, causing the ...
Sumin Kim, James R. Kiniry
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Optimizing water and nitrogen management to reduce basal nitrogen inputs, improve nitrogen uptake and utilization efficiencies, and achieve high yields and low soil nitrate residue in wheat production

Crop and Environment
Excessive basal nitrogen (N) inputs and improper water management limit both wheat yields and N use efficiency. Thus, a field experiment was conducted for two years to evaluate whether optimizing water and N management could reduce basal N inputs ...
Wen Li, Yuyan Fan, Qiu Yang, Wen Lin, Jianfu Xue, Yuechao Wang, Zhiqiang Gao   +6 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Ecological risk from wastewater irrigation: a comprehensive assessment of heavy metal contamination in Egyptian soils

Bulletin of the National Research Centre
Background Continuous irrigation with poor-quality water poses a major threat to soil health and food security through the progressive buildup of potentially toxic elements (PTEs). This study conducted a detailed ecological risk assessment of nickel (Ni),
Monier M. Wahba, Alaa Zaghloul
doaj   +1 more source