Results 41 to 50 of about 27,444 (286)

Sistem Manajemen Proyek Berbasis Website Dengan Metode Kanban

Computer Science
The advancement of digital technology has created a growing demand for systems that support work effectiveness, particularly in project management. The Digital Learning Division at PT.
Florence Aurelia Widjaja, Bhustomy Hakim
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Rancang Bangun Aplikasi Media Pembelajaran Bagi Siswa Penyandang Tuna Rungu Berbasis Android

Techno.Com, 2021
Masyarakat penyandang tuna rungu tentunya mengalami kesulitan saat melakukan komunikasi sehari-hari, terutama bagi para siswa tuna rungu. Sejauh ini, mereka menggunakan bahasa isyarat SIBI dalam kegiatan belajar mengajar.
Addin Aditya, Decya Windri Sukmawati Susanto   +1 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Sistem Monitoring Angkringan Untuk Konsinyasi Barang Berbasis Android

Jurnal Dialektika Informatika, 2021
Angkringan atau merupakan sebuah istilah yang berasal dari Bahasa jawa yaitu angkring, angkring berarti alat dan tempat jualan makanan keliling yang dipikul serta terbentuk melengkung ke atas, yang biasa diliat di berabagai jalan di Indonesia Sebuah ...
Fernanda Hendra Priyono, Arief Susanto, Muhammad Malik Hakim   +2 more
doaj   +1 more source

PELATIHAN PERANGKAT DESA DALAM PENERAPAN METODE WATERFALL PADA SISTEM INFORMASI DESA [PDF]

, 2022
Supiyandi Supiyandi, Chairul Rizal, Muhammad Zen, Muhammad Eka   +3 more
openalex   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Pengembangan Media Pembelajaran Fisika Menggunakan Game Edukasi Pada Kelas Xi Di Madrasah Aliyah Nurul Hidayah Bojonegara

Protek: Jurnal Ilmiah Teknik Elektro, 2021
Verbal delivery of learning and long learning hours causes students to often play games without the knowledge of the teacher during the learning process so that learning outcomes are not optimal to achieve the specified minimum completeness criteria ...
Budi Santosa, Didik Aribowo, Irwanto Irwanto   +2 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source