Results 51 to 60 of about 5,137,558 (305)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A smoothed particle hydrodynamics method for the fluid-structure interaction between waves and flexible net panels: modelling, validation and analysis

Engineering Applications of Computational Fluid Mechanics
With the expansion of mariculture into offshore areas, analysing the hydrodynamic characteristics of net cage structures under wave action has become increasingly important.
Sen-Qi Cui, Chun-Wei Bi
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Numerical simulation on characteristics of wave forces on an incompletely submerged horizontal circular cylinder

Shui kexue jinzhan, 2019
This study investigated the wave forces on an incompletely submerged horizontal circular cylinder under large-amplitude wave action using a viscous fluid numerical wave tank model based on the finite volume method. By analysing the characteristics of the
MAO Hongfei, CHEN Hongzhou
doaj   +1 more source

Nonlinear Wave-Induced Uplift Force onto Pipelines Buried in Sloping Seabeds

Applied Sciences, 2023
In this paper, a two-dimensional numerical model for wave-seabed-pipeline interaction is developed to examine the wave-induced uplift force onto pipelines buried in sloping seabeds.
Lunliang Duan, Bolin Zhan, Linhong Shen, Meiling Fan, Duoyin Wang   +4 more
doaj   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Performance of multilayered porous breakwater under irregular waves having different wave spectrum

Engineering Reports
In this present work, the performance of a two‐layered thick porous breakwater of trapezoidal structure is investigated under the action of irregular waves.
Santanu Kumar Dash, Santanu Koley, Subhendu Paul, Rajdip Dey, Maheswaran S   +4 more
doaj   +1 more source

Simplified calculation of allowable free span length of submarine 'pipelines under action of solitary waves

Shuili Shuiyun Gongcheng Xuebao, 2017
It is important to consider the suspension of the submarine pipelines, analyzing the stability of the submarine pipelines. Because of the complex geological conditions of the seabed, the buried pipelines hung on the seabed are affected by waves.
FU Changjing, LI Guoying, ZHAO Tianlong
doaj   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Monitorização da força da ondulação na base da arriba (Pessegueiro, SW Portugal). Primeiros resultados [PDF]

Finisterra - Revista Portuguesa de Geografia, 1997
MEASUREMENT OF THE WAVE FORCE AT THE CLIFF BASE (PESSEGUEIRO, SW PORTUGAL). FIRST RESULTS. In this article the characteristicsof a new wave force sensor (EWIN) are briefly described.
Mário Neves
doaj   +3 more sources