Results 51 to 60 of about 492,459 (298)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Rapid Localization of Gravitational Wave Sources from Compact Binary Coalescences Using Deep Learning

The Astrophysical Journal, 2023
The mergers of neutron star–neutron star and neutron star–black hole binaries (NSBHs) are the most promising gravitational wave (GW) events with electromagnetic (EM) counterparts.
Chayan Chatterjee, Manoj Kovalam, Linqing Wen, Damon Beveridge, Foivos Diakogiannis, Kevin Vinsen   +5 more
doaj   +1 more source

First search for gravitational waves from the youngest known neutron star [PDF]

, 2010
We present a search for periodic gravitational waves from the neutron star in the supernova remnant Cassiopeia A. The search coherently analyzes data in a 12 day interval taken from the fifth science run of the Laser Interferometer Gravitational-Wave ...
Abadie, J., Abbott, B. P., Abbott, R., Adhikari, Rana X., Ajith, P., Anderson, S. B., Araya, M., Aronsson, M., Aso, Y., Ballmer, S., Betzwieser, J., Billingsley, G., Black, E., Bork, R., Boyle, M., Brooks, A. F., Cannon, K. C., Cepeda, C., Chalermsongsak, T., Chen, Yanbei, Coyne, D. C., Dannenberg, R., Daudert, B., Dergachev, V., DeSalvo, R., Drever, R. W. P., Driggers, J. C., Ehrens, P., Engel, R., Etzel, T., Gustafson, E. K., Hanna, C., Heefner, J., Heptonstall, A., Hodge, K. A., Ivanov, A., Kalmus, P., Kells, W., Keppel, D. G., King, P. J., Kondrashov, V., Kozak, D., Lazzarini, A., Lindquist, P. E., Luan, J., Mageswaran, M., Mailand, K., Mak, C., Maros, E., Marx, J. N., McIntyre, G., Meshkov, S., Mino, Y., Mitra, S., Nash, T., Ogin, G. H., Osthelder, C., Patel, P., Pedraza, M., Robertson, N. A., Sannibale, V., Searle, A. C., Seifert, F., Sengupta, A. S., Singer, A., Smith, M. R., Somiya, K., Stochino, A., Taylor, R., Thorne, K. S., Torrie, C. I., Vallisneri, M., Vass, S., Villar, A., Wallace, L., Ward, R. L., Weinstein, Alan J., Whitcomb, S. E., Willems, P. A., Yamamoto, H., Yeaton-Massey, D., Zhang, L., Zweizig, J.   +82 more
core  

Orbiting binary black hole evolutions with a multipatch high order finite-difference approach [PDF]

, 2009
We present numerical simulations of orbiting black holes for around twelve cycles, using a high-order multipatch approach. Unlike some other approaches, the computational speed scales almost perfectly for thousands of processors.
Duez, Matthew D., Kidder, Lawrence E., Pazos, Enrique, Teukolsky, Saul A., Tiglio, Manuel   +4 more
core   +4 more sources

Wave optics for rotating stars [PDF]

Physical Review D
Gravitational lensing in wave optics is a rich field combining caustic singularities, general relativity and interference phenomena. We present a detailed evaluation of wave optics effects resulting from the frame-dragging of a rotating star modeled by a Lense-Thirring spacetime.
Béatrice Bonga, Job Feldbrugge, Ariadna Ribes Metidieri   +2 more
openaire   +3 more sources

Millimeter-Wave Signature of Strange Matter Stars [PDF]

The Astrophysical Journal, 1998
One of the most important questions in the study of compact objects is the nature of pulsars, including whether they consist of neutron matter or strange quark matter (SQM). However, few mechanisms for distinguishing between these two possibilities have been proposed.
Broderick, John J., Herrin, Eugene T., Krisher, Timothy P., Morgan, David L., Rosenbaum, Doris C., Sher, Marc, Teplitz, Vigdor L.   +6 more
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Reality-infused deep learning for angle-resolved quasi-optical Fourier surfaces

PhotoniX
Optical Fourier surfaces (OFSs), featuring sinusoidally profiled diffractive elements, manipulate light through patterned nanostructures and incident angle modulation.
Wei Chen, Yuan Gao, Yiming Yan, Zhipeng Zhang, Kaibin Chen, Yongxiang Lin, Jiaqing Shen, Mingyong Zhuang, Zhaogang Dong, Jinfeng Zhu   +9 more
doaj   +1 more source

Pre-Supernova Outbursts via Wave Heating in Massive Stars II: Hydrogen-poor Stars [PDF]

, 2018
Pre-supernova (SN) outbursts from massive stars may be driven by hydrodynamical wave energy emerging from the core of the progenitor star during late nuclear burning phases.
Fuller, Jim, Ro, Stephen
core   +3 more sources

Gravitational Waves from Relativistic Stars [PDF]

Progress of Theoretical Physics Supplement, 1999
Stellar pulsations in rotating relativistic stars are reviewed. Slow rotation approximation is applied to solving the Einstein equations. The rotational effects on the non-axisymmetric oscillations are explicitly shown in the polar and axial modes.
openaire   +2 more sources