Results 51 to 60 of about 1,516,944 (293)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Analysis of changes in cotton moisture under the influence of infrared (IR) radiation [PDF]

open access: yesBIO Web of Conferences
Current cotton drying technology has a negative impact on product quality due to the use of high temperatures and very low energy efficiency. In the literature on the research on their elimination, information on heat generation from fuel by traditional ...
Kayumov Abdul-Malik   +2 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Transcranial Laser Stimulation Research—A New Helmet and First Data from Near Infrared Spectroscopy

open access: yesMedicines, 2018
This editorial adopts a future-oriented technology. It describes a new modern helmet for transcranial laser stimulation and a way to quantify effects of this possible therapeutical method using near-infrared spectroscopy.
Gerhard Litscher
doaj   +1 more source

Wavelength of Experimental LEDS: Hardness, Elastic Modulus, Degree of Conversion and Temperature Rise of a Microhybrid Composite [PDF]

open access: yesMaterials Research, 2015
The aim of this study was to evaluate the effect of different peak wavelengths (450nm, 468nm and 490nm) of experimental LEDs on hardness, elastic modulus, degree of conversion and temperature rise of a microhybrid resin composite – Venus® (Heraeus Kulzer)
Ana Paula Bonilauri Ferreira   +5 more
doaj   +1 more source

Red-Shift (2-Hydroxyphenyl)-Benzothiazole Emission by Mimicking the Excited-State Intramolecular Proton Transfer Effect

open access: yesFrontiers in Chemistry, 2021
Novel strategies to optimize the photophysical properties of organic fluorophores are of great significance to the design of imaging probes to interrogate biology.
Yong Ren, Lei Zhou, Lei Zhou, Xin Li
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Comparison of cutting and coagulation properties of 1.56 and 1.94 µm fiber lasers and a 0.98 µm semiconductor laser

open access: yesБюллетень сибирской медицины, 2022
Aim of the study was to compare the cutting and coagulation properties of 1.56 and 1.94 μm fiber lasers with those of a 0.98 μm semiconductor laser.Materials and methods. A comparative study of the biological effects of 1.56 and 1.94 µm lasers and a 0.98
M. A. Ryabova   +5 more
doaj   +1 more source

Thin film wavelength converters for photonic integrated circuits

open access: yes, 2016
Quasi-phase-matched (QPM) wavelength converters are highly desirable for emerging nonlinear optics applications in photonic integrated circuits, but available waveguide and quasi-phase-matching technologies have so far constrained their realization.
L. Chang   +5 more
semanticscholar   +1 more source

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