Results 81 to 90 of about 1,495,802 (347)
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
Optics Express, 2015 We propose and demonstrate a tunable and switchable dual-wavelength ultra-fast Tm-doped fiber laser. The tunability is based on nonlinear polarization evolution (NPE) technique in a passively mode-locked laser cavity.
Zhiyu Yan +6 more
semanticscholar +1 more source
Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam +6 more
wiley +1 more source
Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen +18 more
wiley +1 more source
Актуальні питання суспільних наук та історії медицини, 2017 Бирюкова Т.В., Олар Е.И., Федив В.И., Галушко К.С. История внедрения лазерних технологий в медицине. В статье рассмотрены основные исторические этапы развития лазерных технологий и их внедрения в медицине на основе достижений физики. Цель исследования.
Тетяна БІРЮКОВА +3 more
doaj +1 more source
Optimum wavelength for long-wavelength LED systems
Electronics Letters, 1983 The bandwidth limitations due to material and modal dispersion are calculated for long-wavelength LED systems using measured attenuation and group delay characteristics for fibres of two different types. The data presented allow the establishment of selection criteria for LEDs used in 140 Mbit/s systems.
openaire +2 more sources
LIN28B Promotes Cancer Cell Dissemination and Angiogenesis
Advanced Biology, EarlyView.Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo +8 more
wiley +1 more source
CANDELS MULTI-WAVELENGTH CATALOGS: SOURCE DETECTION AND PHOTOMETRY IN THE GOODS-SOUTH FIELD [PDF]
, 2013 We present a UV to mid-infrared multi-wavelength catalog in the CANDELS/GOODS-S field, combining the newly obtained CANDELS HST/WFC3 F105W, F125W, and F160W data with existing public data.
Yicheng Guo +37 more
semanticscholar +1 more source
Advanced Biology, EarlyView.This study investigates the photosensitizing potential of Passiflora cincinnata in Antimicrobial Photodynamic Therapy (aPDT) against skin infection caused by Methicillin‐resistant Staphylococcus aureus (MRSA) in a senescent murine model. The P. cincinnata exhibits antimicrobial activity, with reduced bacterial load, lower leukocyte infiltration, and ...
Caroline Vieira Gonçalves +14 more
wiley +1 more source
Advanced Biology, EarlyView.Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams +7 more
wiley +1 more source