Results 81 to 90 of about 186,321 (307)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Helen Wax, Fund for Needy Children, 2004
, 2004 In this interview, Helen G. Wax describes her and her husband Rabbi James Wax's activism work during the 1950s. She recounts how she helped organize and implement the Fund for Needy Children and the work that many members of the Memphis Jewish community ...
core
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Oligosaccharide release from frozen and paraffin-wax-embedded archival tissues.
, 1996 Altered glycosylation is a feature of many solid tissue diseases such as ulcerative colitis, Crohn's disease, cancer, and connective tissue disorders. Conventionally, oligosaccharide changes have been studied by immunohistochemical techniques.
Streets, A.J. +4 more
core +1 more source
An In-depth Experimental Study of Wax Deposition in Pipelines [PDF]
Shale oils are highly paraffinic and, consequently, can create wax deposits that foul pipelines during transportation. Several factors must be considered when designing pipelines or treatmentprograms that prevent wax deposition: including chemical ...
Raffo, Pablo Alejandro +5 more
core +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Rabbi Wax Speaks to Mayor Loeb, 1968
, 1968 This is a speech given by Rabbi James Wax to Mayor Henry Loeb of Memphis. Wax voices his anger, calling out injustice and opression and claiming that the hightest laws are the laws of ...
core
Colloids and InterfacesIn this study, cationic surfactant cetyltrimethylammonium bromide (CTAB) and anionic surfactant sodium bis(2-ethylhexyl) sulfosuccinate (AOT) are employed to systematically investigate surface and wetting properties on hydrophobic surfaces, specifically ...
Sujit Kumar Shah +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source