Results 61 to 70 of about 2,441,236 (286)

Impact of heterogeneities on lateral penumbra in uniform scanning proton therapy [PDF]

, 2013
Purpose: In the treatment planning of uniform scanning proton therapy, an aperture block is designed for each beam with a margin, which typically includes the lateral penumbra measured in water (homogenous) medium.
Rana, Suresh; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City, Singh, Hardev; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City   +1 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Mepolizumab as an effective treatment for Kimura's disease associated with ulcerative colitis: A case report

Journal of Family Medicine and Primary Care, 2019
Kimura's disease was first described by Kimura and Sceto in China in 1937. Kimura disease is a chronic inflammatory disorder of idiopathic etiology.
Faisal Al Shammari, Abdulrahman Nasiri, Mohammed Alkhathami, Fahad Alawfi, Mohammed Alfifi, Eqab Al Otaibi   +5 more
doaj   +1 more source

The composition of wax and oil in green coffee beans [PDF]

, 1976
Methods for the isolation of wax and oil from green coffee beans were studied and a method for the quantitative extraction of coffee oil from the beans was introduced.
Folstar, P.
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Is wax equivalent to tissue in electron conformal therapy planning? A Monte Carlo study of material approximation introduced dose difference

Journal of Applied Clinical Medical Physics, 2013
With CT‐based Monte Carlo (MC) dose calculations, material composition is often assigned based on the standard Hounsfield unit ranges. This is known as the density threshold method. In bolus electron conformal therapy (BolusECT), the bolus material, machineable wax, would be assigned as soft tissue and the electron density is assumed equivalent to soft
Zhang, Ray R., Feygelman, Vladimir, Harris, Eleanor R., Rao, Nikhil, Moros, Eduardo G., Zhang, Geoffrey G.   +5 more
openaire   +2 more sources

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Traditional Chinese Medicine Mud Inunction Combined with Wax Therapy in Treating 30 Cases of Spastic Cerebral Palsy Children with Spasticities of Plantar Flexor

康复学报, 2016
Objective:To observe the curative effects of traditional Chinese medicine mud inunction combined with wax therapy on relieving plantar flexor spasms and reducing muscle tension in children with spastic cerebral palsy.Methods:60 spastic cerebral palsy ...
Xixi WANG, Bo LIU, Qiang TANG, Dongliang XIANG, Xingyue FAN   +4 more
doaj  

Inhibitor-Wax Interactions and Wax Crystallization: New Experimental Approaches and Techniques

, 2018
Issues related to wax crystallization are one of the major challenges faced during crude oil production. Wax inhibitors and pour point depressants (PPD) are in common use for wax prevention, as they can delay gelling and ensure low enough crude oil ...
Ruwoldt, Jost
core   +1 more source