Results 31 to 40 of about 166,071,484 (282)
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Zhongguo dizhi zaihai yu fangzhi xuebao, 2021 In order to further improve the safety and stability of railway tunnels with weak surrounding rocks during earthquake, the Xinping tunnel at Yumo Railway was taken as an example and, to study the effect of pile-raft seismic measures at the tunnel opening
Guangyao CUI, Pengyu LI, Qingjian WANG
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Are CO2 emissions converging in the European Union? Policy implications
Notas Económicas, 2019 This paper focuses on the process of convergence in per capita CO2 emissions that would occur if the measures taken by the European Union to meet the Kyoto Protocol commitments had been effective.
Rafael Morales-Lage +2 more
doaj +1 more source
Boosting for Distributed Online Convex Optimization
Tsinghua Science and Technology, 2023 Decentralized Online Learning (DOL) extends online learning to the domain of distributed networks. However, limitations of local data in decentralized settings lead to a decrease in the accuracy of decisions or models compared to centralized methods ...
Yuhan Hu +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
On weak convergence of long-range-dependent traffic processes
, 1999 A possible model for communication traffic is that the amount of work arriving in successive time intervals is jointly Gaussian. This model seems to fly in the face of certain obvious and characteristic features of real traffic, such as the fact that it ...
Addie, R. G.
core +1 more source
On the Generalizations of Universality Theorem for L-Functions of Elliptic Curves
Jaunųjų Mokslininkų Darbai, 2017 In the paper, the continuous type’s universality theorem for L-functions of elliptic curves is discussed and its generalizations in three directions – for positive integer powers and derivatives of L-functions of elliptic curves as well as the weighted ...
Virginija Garbaliauskienė
doaj +1 more source