Results 41 to 50 of about 36,048 (260)

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Application of Stochastic Elements in the Universality of the Periodic Zeta-Function: The Case of Short Intervals

Axioms
Let a={am:m∈N} be a multiplicative periodic sequence of complex numbers.
Marius Grigaliūnas, Antanas Laurinčikas, Darius Šiaučiūnas   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Joint discrete approximation of analytic functions by shifts of Lerch zeta-functions

Mathematical Modelling and Analysis
The Lerch zeta-function depends on two real parameters λ and  and, for σ > 1, is defined by the Dirichlet series , and by analytic continuation elsewhere. In the paper, we consider the joint approximation of collections of analytic functions by discrete
Antanas Laurinčikas, Toma Mikalauskaitė, Darius Šiaučiūnas   +2 more
doaj   +1 more source

A Discrete Limit Theorem for L-Functions of Elliptic Curves

Jaunųjų Mokslininkų Darbai, 2018
In the paper, we prove the discrete limit theorem in the sense of the weak convergence of probability measures in the space of analytic on DV = {s ∈ C : 1 < σ < 3/2, |t|  0 be a fixed real number such that exp {2πk/h} is an irrational number for all k∈Z\{
Virginija Garbaliauskienė, Antanas Garbaliauskas   +1 more
doaj   +1 more source

Weak integral convergence theorems and operator measures [PDF]

Pacific Journal of Mathematics, 1984
In the first part of this paper (submitted in 1978 and revised in 1983), an integration theory is outlined for (certain measurable) functions with values in a locally convex (l.c.) space X with respect to a measure \(\mu\) with values in the continuous linear operators L(X,Y) from X into some (quasi-complete) l.c. space Y such that \(\mu\) (\(\cdot)x\)
Smith, William V., Tucker, Don H.
openaire   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Joint approximation of analytic functions by the shifts of Hurwitz zeta-functions in short intervals

Open Mathematics
In the article, we obtain that, for algebraically independent over Q{\mathbb{Q}} parameters α1,…,αr{\alpha }_{1},\ldots ,{\alpha }_{r}, there are infinitely many shifts (ζ(s+iτ,α1),…,ζ(s+iτ,αr))\left(\zeta \left(s+i\tau ,{\alpha }_{1}),\ldots ,\zeta ...
Laurinčikas Antanas, Šiaučiūnas Darius   +1 more
doaj   +1 more source