Results 61 to 70 of about 417,817 (243)
, 2007 The coupling of chiral fermions to gravity makes use only of the selfdual SU(2) subalgebra of the (complexified) SO(3,1) algebra. It is possible to identify the antiselfdual subalgebra with the SU(2)_L isospin group that appears in the Standard Model, or
Nesti, F., Percacci, R.
core +3 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Diagnosing atmosphere–land feedbacks in CMIP5 climate models
Environmental Research Letters, 2012 Human-made transformations to the environment, and in particular the land surface, are having a large impact on the distribution (in both time and space) of rainfall, upon which all life is reliant.
C J R Williams, R P Allan, D R Kniveton
doaj +1 more source
Dualities in fractional statistics
, 2004 We first reobtain in a simpler way the Haldane fractional statistics at thermal equilibrium using an interpolation argument. We then show that the mean occupation number for fractional statistics is invariant to a group of duality transformations, a ...
Buyukkihc F., Einstein A., M. I. Beciu
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
International Journal of ThermofluidsThe increasing demand for sustainable and long-lasting energy sources has highlighted the limitations of conventional flat plate collectors (FPCs), particularly their reduced efficiency under low solar radiation and weak fluid heat transfer capabilities.
T. Sathish, A. Johnson Santhosh
doaj +1 more source
WAYS OF IMPLEMENTING A COMPLEX APPROACH TO INCREASE THE COMPETITIVENESS OF UKRAINE [PDF]
European Vector of Economic DevelopmentThe study focuses on examining the key factors influencing the competitive state of Ukraine’s socio-economic model at the current stage of development.
Alisa S. Mahdich +2 more
doaj +1 more source
Mathematical structure and physical content of composite gravity in weak-field approximation
, 2020 The natural constraints for the weak-field approximation to composite gravity, which is obtained by expressing the gauge vector fields of the Yang-Mills theory based on the Lorentz group in terms of tetrad variables and their derivatives, are analyzed in
Öttinger, Hans Christian
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source