Results 61 to 70 of about 46,236 (223)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Prevalence of congenital pathology in populations with different genetic and demographic structure

open access: yesБіологічні студії, 2018
The article presents the results of studing the dynamics of some genetic and demographic indicators of the regional populations of the Kherson region (the level of interethnic and homolocal mono-ethnic Ukrainian marriages, the endogamy index) during the ...
E. G. Lanovenko
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Alteration Mechanisms and Classification Criteria of Hercynian Mid-term Granite in the North Tianshan Mountains [PDF]

open access: yes长江科学院院报
[Objective] This study aims to address the limitations of traditional quantitative classification methods for altered granites, which often lead to coarse grade divisions and significant discrepancies in rock degradation between adjacent grades. Focusing
CHEN Li-xiang, DING Xiu-li, HUANG Shu-ling, HUANG Kang
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Monsoonal imprint on late Quaternary landscapes of the Rub’ al Khali Desert

open access: yesCommunications Earth & Environment
Abundant geomorphological, biological, and isotopic records show that Arabia repeatedly underwent significant climate-driven environmental changes during late Quaternary humid periods.
Abdallah S. Zaki   +17 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Influence of iron-based salts and silica nanoparticles on the phase transition, morphology, and photocatalytic activity of electrospun TiO2 nanofibers

open access: yesNext Materials
Electrospun TiO2 nanofibers (NFs) were modified using different dopant chemistries to investigate the influence of iron-based salts and silica nanoparticles on phase composition, microstructure, and photocatalytic performance.
Nasser A.M. Barakat   +3 more
doaj   +1 more source

An Analysis of the Antecedents and Consequences of Knowledge Absorptive Capacity in the Insurance Industry [PDF]

open access: yesIranian Journal of Insurance Research
BACKGROUND AND OBJECTIVES: Due to the data‑driven and knowledge‑based nature of insurance industry, the development of this industry depends on enhancing its absorptive capacity, i.e., the ability to acquire, analyze, combine, and apply knowledge ...
Shabnam Refoua   +1 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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