Results 91 to 100 of about 528,108 (265)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Chaotic Dynamics Analysis of Magnetocardiography Signals for Early Detection of Myocardial Ischemia

Bioengineering
The heart exhibits inherently nonlinear and chaotic electrical dynamics, making the early detection of myocardial ischemia (MI) challenging using traditional electrocardiography (ECG) or standard magnetocardiography (MCG).
Keyi Li, Xiangyang Zhou, Yuchen Liu, Jiaojiao Pang, Rui Shang, Yadan Zhang, Yangyang Cui, Dong Xu, Min Xiang   +8 more
doaj   +1 more source

Demonstration of a New Characterization Method for Weak Measurement. [PDF]

Front Chem, 2022
Xu Y, Shi L, Zhou C, Li Z, Guan T, Xing X, Liu L, He Y.   +7 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Transient dynamics of magneto-optic rotation with elliptically polarized light

Results in Physics
In this paper, we analyze the transient behavior of nonlinear magneto-optical rotation in a 87Rb vapor cell. Our focus is on optimizing the optical rotation signal by identifying influential factors.
Binbin Zhao, Junjian Tang, Lin Li, Yaohua Zhang, Yueyang Zhai   +4 more
doaj   +1 more source

Quantum Gaussian channels with weak measurements

Quantum Information and Computation, 2015
In this paper we perform a novel analysis of quantum Gaussian channels in the context of weak measurements. Suppose Alice sends classical information to Bob using a quantum channel. Suppose Bob is allowed to use only weak measurements, what would be the channel capacity? We formulate weak measurement theory in these terms and discuss the above question.
Boaz Tamir, Eliahu Cohen
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Comprehensive analysis of the influence of magnetic field gradients on single-beam SERF atomic magnetometer

Results in Physics
Magnetic field gradients interfere with the coherence of the atomic ensemble and degrade the performance of the spin-exchange relaxation-free (SERF) atomic magnetometer.
Jiajie Li, Ying Liu, Renjie Li, Qian Cao, Tianwei Zhou, Yueyang Zhai   +5 more
doaj   +1 more source

Nanophotonic-assisted precision enhancement of weak measurement using spin Hall effect of light. [PDF]

Nanophotonics, 2022
Kim M, Lee D, Kim Y, Rho J.
europepmc   +1 more source

Weak values and weak coupling maximizing the output of weak measurements [PDF]

Annals of Physics, 2014
In a weak measurement, the average output $\langle o\rangle$ of a probe that measures an observable $\hat{A}$ of a quantum system undergoing both a preparation in a state $ρ_i$ and a postselection in a state $E_\mathrm{f}$ is, to a good approximation, a function of the weak value $A_w=\mathrm{Tr} [E_f \hat{A} ρ_i]/\mathrm{Tr}[E_fρ_i]$, a complex number.
openaire   +2 more sources