Results 81 to 90 of about 528,108 (265)
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Investigating the Coherence Between Motor Cortex During Rhythmic Finger Tapping Using OPM-MEG
Optically pumped magnetometer OPM-MEG has the potential to replace the traditional low-temperature superconducting quantum interference device SQUID-MEG.
Hao Lu +4 more
doaj +1 more source
A compact weak measurement to observe the spin Hall effect of light. [PDF]
Kim M.
europepmc +1 more source
On Weak Compactness in Spaces of Measures
It is proved that a weak\(^*\) compact subset \(A\) of scalar measures on a \(\sigma\)-algebra is weakly compact if and only if there exists a nonnegative scalar measure \(\lambda\) such that each measure in \(A\) is \(\lambda\)-continuous (such a measure \(\lambda\) is called a control measure for \(A\)).
openaire +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Measuring Phase–Amplitude Coupling Effect with OPM-MEG
Optically pumped magnetometers (OPMs) present a promising opportunity to advance magnetoencephalography (MEG), enhancing the accuracy of neuronal activity recordings due to their high spatiotemporal resolution.
Yong Li +7 more
doaj +1 more source
Weak-measurement-induced heating in Bose-Einstein condensates. [PDF]
Altuntaş E, Spielman IB.
europepmc +1 more source
Weak values beyond weak measurement
5 pages, 2 figures, v2 updated to address anonymous and friendly ...
openaire +2 more sources

