Results 61 to 70 of about 528,108 (265)

Non-statistical weak measurements [PDF]

open access: yesSPIE Proceedings, 2007
Non-statistical weak measurements yield weak values that are outside the range of eigenvalues and are not rare, suggesting that weak values are a property of every pre-and-post-selected ensemble. They also extend the applicability and valid regime of weak values.
Tollaksen, Jeff, Aharonov, Yakir
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Repairbads: An automatic and adaptive method to repair bad channels and segments for OPM-MEG

open access: yesNeuroImage
The optically pumped magnetometer (OPM) based magnetoencephalography (MEG) system offers advantages such as flexible layout and wearability. However, the position instability or jitter of OPM sensors can result in bad channels and segments, which ...
Fulong Wang   +8 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Weak Value Measurement with an Incoherent Measuring Device [PDF]

open access: yesConference on Lasers and Electro-Optics 2010, 2010
6 pages, 4 figures, corrected typo (email address)
Cho, YW, Lim, HT, Ra, YS, Kim, YH
openaire   +4 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Weak Value and Weak Measurements

open access: yes, 2009
The weak value of a variable O is a description of an effective interaction with that variable in the limit of weak coupling. It is particularly important for a pre- and post-selected quantum system.
openaire   +2 more sources

Weak measurements for reutilizing entanglement [PDF]

open access: yes, 2020
Weak measurements are a relevant tool for quantum information because they allow tuning the disturbance on the observed state and the amount of information extracted from it. They can be used to harness repeatedly a quantum resource from the same state, thus boosting the performance of many protocols.
Foletto, Giulio   +7 more
openaire   +2 more sources

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