Results 111 to 120 of about 528,108 (265)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

An Optical Chiral Sensor Based on Weak Measurement for the Real-Time Monitoring of Sucrose Hydrolysis. [PDF]

Sensors (Basel), 2021
Li D, Weng C, Ruan Y, Li K, Cai G, Song C, Lin Q.   +6 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Decoding N400m Evoked Component: A Tutorial on Multivariate Pattern Analysis for OP-MEG Data

Bioengineering
Multivariate pattern analysis (MVPA) has played an extensive role in interpreting brain activity, which has been applied in studies with modalities such as functional Magnetic Resonance Imaging (fMRI), Magnetoencephalography (MEG) and ...
Huanqi Wu, Ruonan Wang, Yuyu Ma, Xiaoyu Liang, Changzeng Liu, Dexin Yu, Nan An, Xiaolin Ning   +7 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

An Exploration on Aperiodic Activities and Transient Oscillations During Semantic Processing: A Study With Wearable MEG

IEEE Transactions on Neural Systems and Rehabilitation Engineering
The processing of semantic information is pivotal in language cognition. However, there is a scarcity of research exploring the semantic-related patterns associated with aperiodic and transient periodic brain activities. In this study, recently developed
Xiaoyu Liang, Yuyu Ma, Ruonan Wang, Huanqi Wu, Changzeng Liu, Fuzhi Cao, Nan An, Min Xiang, Yueyang Zhai, Xiaolin Ning   +9 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Advances of magnetocardiography in application of adult and fetal cardiac diseases

Frontiers in Cardiovascular Medicine
Magnetocardiography (MCG) is a highly sensitive, non-invasive, and functional imaging technique that records and examines magnetic fields generated by the electrical activity of the heart to reflect cardiac electrophysiological changes, including the ...
Junting Li, Junting Li, Yaqian Shen, Chengxing Shen, Xiaolin Ning, Xiaolin Ning, Xiaolin Ning, Min Xiang, Min Xiang, Min Xiang   +9 more
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Extended homogeneous field correction method based on oblique projection in OPM-MEG

NeuroImage
Optically pumped magnetometer-based magnetoencephalography (OPM-MEG) is an novel non-invasive functional imaging technique that features more flexible sensor configurations and wearability; however, this also increases the requirement for environmental ...
Fulong Wang, Fuzhi Cao, Yujie Ma, Ruochen Zhao, Ruonan Wang, Nan An, Min Xiang, Dawei Wang, Xiaolin Ning   +8 more
doaj   +1 more source