Results 111 to 120 of about 1,749,039 (283)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Distributed photonic variational quantum eigensolver with parameterized weak measurements
npj Quantum InformationWe demonstrate a two-qubit variational quantum eigensolver (VQE) implementation using two spatially separated single-photon processors connected via a 3 km optical fiber network.
Donghwa Lee +6 more
doaj +1 more source
Weak values beyond weak measurement
, 2013 5 pages, 2 figures, v2 updated to address anonymous and friendly ...
openaire +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Weak continuous measurements require more work than strong ones
Physical Review ResearchUnderstanding the energy cost of quantum measurement process and its connection to the measurement performance faces the challenge of modeling the objectification process.
Lorena Ballesteros Ferraz, Cyril Elouard
doaj +1 more source
Can a Future Choice Affect a Past Measurement’s Outcome?
EPJ Web of Conferences, 2014 An EPR experiment is studied where each particle undergoes a few weak measurements along some pre-set spin orientations, whose outcomes are individually recorded.
Aharonov Y. +3 more
doaj +1 more source
Super Quantum Discord with Weak Measurements
, 2013 Weak measurements cause small change to quantum states, thereby opening up the possibility of new ways of manipulating and controlling quantum systems. We ask, can weak measurements reveal more quantum correlation in a composite quantum state?
Pati, Arun Kumar, Singh, Uttam
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Quantum Gaussian channels with weak measurements
Quantum Information and Computation, 2015 In this paper we perform a novel analysis of quantum Gaussian channels in the context of weak measurements. Suppose Alice sends classical information to Bob using a quantum channel. Suppose Bob is allowed to use only weak measurements, what would be the channel capacity? We formulate weak measurement theory in these terms and discuss the above question.
Boaz Tamir, Eliahu Cohen
openaire +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source