Results 101 to 110 of about 3,954,992 (288)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

The nonnegative weak solution of a degenerate parabolic equation with variable exponent growth order

open access: yesBoundary Value Problems, 2020
A degenerate parabolic equation of the form ( | v | β − 1 v ) t = div ( b ( x , t ) | ∇ v | p ( x , t ) − 2 ∇ v ) + ∇ g → ⋅ ∇ γ → ( v ) $$\bigl( \vert v \vert ^{\beta-1}v\bigr)_{t}= \operatorname{div} \bigl(b(x,t) \vert \nabla v \vert ^{p(x,t)-2}\nabla v
Huashui Zhan
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Approximate symmetry reduction approach: infinite series reductions to the KdV-Burgers equation

open access: yes, 2008
For weak dispersion and weak dissipation cases, the (1+1)-dimensional KdV-Burgers equation is investigated in terms of approximate symmetry reduction approach.
Jiao, Xiaoyu   +3 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Weak homogeneity of lattice ordered groups [PDF]

open access: yesCzechoslovak Mathematical Journal, 2007
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Weak Solutions for a Second Order Dirichlet Boundary Value Problem on Time Scale

open access: yesJournal of Applied Mathematics, 2013
We adopt the Leray-Schauder degree theory and critical point theory to consider a second order Dirichlet boundary value problem on time scales and obtain some existence theorems of weak solutions for the previous problem.
Wandong Lou
doaj   +1 more source

Maximal matroids in weak order posets

open access: yesJournal of Combinatorial Theory, Series B
typographical corrections, exposition ...
Bill Jackson, Shin-ichi Tanigawa
openaire   +3 more sources

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

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