Results 81 to 90 of about 117,653 (287)

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Critical Behavior of Coupled q-state Potts Models under Weak Disorder

open access: yes, 1997
We investigate the effect of weak disorder on different coupled $q$-state Potts models with $q\le 4$ using two loops renormalisation group. This study presents new examples of first order transitions driven by randomness.
Cardy J. L.   +8 more
core   +1 more source

Weak convergence of a random walk in a random environment [PDF]

open access: yesCommunications in Mathematical Physics, 1982
Let π i (x),i=1,...,d,x∈Z d , satisfy π i (x)≧α>0, and π1(x)+...+π d (x)=1. Define a Markov chain onZ d by specifying that a particle atx takes a jump of +1 in thei th direction ...
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Piezoelectric Poly(vinylidene fluoride) (PVDF) Polymer-Based Sensor for Wrist Motion Signal Detection

open access: yesApplied Sciences, 2018
In this paper, a sensor based on polyvinylidene fluoride (PVDF) piezoelectric thin film was designed and fabricated to detect wrist motion signals. A series of dynamic experiments have been carried out, including the contrast experiments of different ...
Yaohui Hu   +5 more
doaj   +1 more source

Bond-randomness-induced Neel order in weakly coupled antiferromagnetic spin chains

open access: yes, 2003
Quasi-one-dimensional antiferromagnetic (AF) quantum spin systems show a wide range of interesting phenomena such as the spin-Peierls transition and disorder driven long range ordering.
A. Chubukov   +46 more
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Are Markets Truly Efficient? Experiments Using Deep Learning Algorithms for Market Movement Prediction

open access: yesAlgorithms, 2018
We examine the use of deep learning (neural networks) to predict the movement of the S&P 500 Index using past returns of all the stocks in the index. Our analysis finds that the future direction of the S&P 500 index can be weakly predicted by the
Sanjiv R. Das   +2 more
doaj   +1 more source

Destruction of bulk ordering by surface randomness

open access: yes, 2002
We demonstrate that the arbitrarily weak quenched disorder on the surface of a system of continuous symmetry destroys long range order in the bulk, and, instead, quasi-long range order emerges.
A. I. Larkin   +5 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

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