Results 61 to 70 of about 14,610 (258)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Inverting weak random operators [PDF]

open access: yesRandom Operators and Stochastic Equations, 2019
Abstract We analyze two weak random operators, initially motivated from processes in random environment. At first glance, these operators are ill-defined, but using bilinear forms, one can deal with them in a rigorous way. This point of view can be found, for instance, in [A. V. Skorohod, Random Linear Operators, Math. Appl. (Sov. Ser.
Gutierrez-Pavón, Jonathan   +1 more
openaire   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Piezoelectric Poly(vinylidene fluoride) (PVDF) Polymer-Based Sensor for Wrist Motion Signal Detection

open access: yesApplied Sciences, 2018
In this paper, a sensor based on polyvinylidene fluoride (PVDF) piezoelectric thin film was designed and fabricated to detect wrist motion signals. A series of dynamic experiments have been carried out, including the contrast experiments of different ...
Yaohui Hu   +5 more
doaj   +1 more source

Weak convergence of a random walk in a random environment [PDF]

open access: yesCommunications in Mathematical Physics, 1982
Let π i (x),i=1,...,d,x∈Z d , satisfy π i (x)≧α>0, and π1(x)+...+π d (x)=1. Define a Markov chain onZ d by specifying that a particle atx takes a jump of +1 in thei th direction ...
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Are Markets Truly Efficient? Experiments Using Deep Learning Algorithms for Market Movement Prediction

open access: yesAlgorithms, 2018
We examine the use of deep learning (neural networks) to predict the movement of the S&P 500 Index using past returns of all the stocks in the index. Our analysis finds that the future direction of the S&P 500 index can be weakly predicted by the
Sanjiv R. Das   +2 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Weak Saturation Numbers in Random Graphs

open access: yesJournal of Graph Theory
ABSTRACT For two given graphs and , a graph is said to be weakly ‐saturated if is a spanning subgraph of which has no copy of as a subgraph and one can add all edges in to in some order so that a new copy of is created at each step. The weak saturation number is the minimum number of edges of a weakly ‐saturated graph.
Kalinichenko, Olga   +3 more
openaire   +2 more sources

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