Results 81 to 90 of about 1,709,745 (295)
Some exact formulae of the expectation values and probability densities in a weak measurement for an operator ${\bf A}$ which satisfies the property ${\bf A}^{2}=1$ are derived. These formulae include all-order effects of the unitary evolution due to the
Atsushi Nishizawa +4 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Correlation functions at small quark masses with overlap fermions
We report on recent work on the determination of low-energy constants describing Delta{S}=1 weak transitions, in order to investigate the origins of the Delta{I}=1/2 rule.
Bietenholz +13 more
core +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Weak Signal Detection Algorithm Based on Particle Filtering [PDF]
In the traditional particle filter algorithm, there exist problems such as poor robustness against noise and clutter, and difficulty in balancing the detection probability and false alarm probability.
Mao Senpeng, Wang Pengfei, Chen Wei, Guo Lei
doaj +1 more source
Discovery of a very weak magnetic field on the Am star Alhena
Alhena ($\gamma$ Gem) was observed in the frame of the BRITE (BRIght Target Explorer) spectropolarimetric survey, which gathers high resolution, high signal-to-noise, high sensitivity, spectropolarimetric observations of all stars brighter than V=4 to ...
Blazère, Aurore +2 more
core +3 more sources
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Research of power line communication based on independent component analysis
According to channel characteristics of power line communication(PLC),a scheme of applying independent component analysis to PLC system was proposed.The system model was constructed by the transmission characteristic of power line.The experiment and ...
GAO Qiang +3 more
doaj
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source

