Results 101 to 110 of about 8,223,685 (372)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Quantum lock-in measurement of weak alternating signals

Quantum Frontiers
The detection of weak time-dependent alternating signals in a strongly noisy background is an important problem in physics and a critical task in metrology. Quantum lock-in amplifier can extract alternating signals within extreme noises by using suitable
Min Zhuang, Sijie Chen, Jiahao Huang, Chaohong Lee   +3 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The strongness of weak signals: self-reference and paradox in anticipatory systems

, 2016
Social sciences are experiencing an anticipatory turn. A core issue of this turn are the so-called ‘weak signals’. In order to speak of this type of signals, we must use the distinction between weak and strong.
Alberto Cevolini
semanticscholar   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Empirical investigation on the dependence of TCP downstream throughput on SNR in an IEEE802.11b WLAN system

Journal of King Saud University: Engineering Sciences, 2017
The dependence of TCP downstream throughput (TCPdownT) on signal to noise ratio (SNR) in an IEEE802.11b WLAN system was investigated in various environments and varieties of QoS traffic. TCPdownT was measured for various SNR observed.
Ikponmwosa Oghogho, Fredrick O. Edeko, Joy Emagbetere   +2 more
doaj   +1 more source

Identifying weak signals to prepare for uncertainty in the energy sector. [PDF]

Heliyon, 2023
Gilmore N, Koskinen I, Burr P, Obbard E, Sproul A, Konstantinou G, Bilbao J, Daiyan R, Kay M, Corkish R, Macgill I, Lovell E, Menictas C, Bruce A.   +13 more
europepmc   +1 more source

Weak positive cloud-to-ground flashes in Northeastern Colorado [PDF]

The frequency distributions of the peak magnetic field associated with the first detected return stroke of positive and negative cloud-to-ground (CG) flashes were studied using lightning data from northeastern Colorado.
Garcia-Miguel, Juan A., Holle, Ronald L., Lopez, Raul E., Maier, Michael W.   +3 more
core   +1 more source

Weak temporal signals can synchronize and accelerate the transition dynamics of biopolymers under tension

, 2012
In addition to thermal noise, which is essential to promote conformational transitions in biopolymers, cellular environment is replete with a spectrum of athermal fluctuations that are produced from a plethora of active processes.
Bell, Bustamante, C. Hyeon, Cecconi, Doering, Dudko, Gammaitoni, Hyeon, H  nggi, Kim, Liphardt, McDonnell, Onoa, Onuchic, Pizzolato, Sanchez, Shaevitz, Shin, Smith, Stigler, Strick, Thirumalai, Visscher, W. K. Kim, W. Sung, Wen, Woodside, Zhou   +27 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source