Results 121 to 130 of about 4,913,850 (297)
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Stochastic very weak solution to parabolic equations with singular coefficients [PDF]
A class of stochastic parabolic equations with singular potentials is analysed in the chaos expansion setting where the Wick product is used to give sense to the product of generalized stochastic processes.
Gordić, Snežana +2 more
core +2 more sources
MathematicsIn this paper, we have undertaken the challenging and novel task of establishing the existence of weak solutions for four types of hyperbolic Kirchhoff-type problems: the classical hyperbolic Kirchhoff problem, the problem with a free boundary, the ...
Fatima Ezahra Bentata +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Uniqueness of global weak solution for some hyperbolic conservation system [PDF]
, 2014 En el presente trabajo se estudia la unicidad de soluciones entrópicas para los problemas de Riemann y Cauchy asociados al sistema de relajación de Suliciu donde el dato inicial satisface las condiciones H1 y H2.
De la Cruz Guerrero, Richard Alexander
core
Unilateral problems for the Klein-Gordon operator with nonlinearity of Kirchhoff-Carrier type
Electronic Journal of Differential Equations, 2015 This work concerns the unilateral problem for the Klein-Gordon operator $$ \mathbb{L}=\frac{\partial^2 u}{\partial t^2}-M(|\nabla u|^2)\Delta u+M_1(|u|^2)u-f.
Carlos Raposo +3 more
doaj
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Voluntary Environmental Agreements when Regulatory Capacity Is Weak [PDF]
Voluntary agreements (VAs) negotiated between environmental regulators and industry are increasingly popular. However, little is known about whether they are likely to be effective in developing and transition countries, where local and federal ...
Blackman, Allen +2 more
core