Results 101 to 110 of about 2,506,197 (280)
Uniqueness of weak solution for nonlinear elliptic equations in divergence form
International Journal of Mathematics and Mathematical Sciences, 2000 We study the uniqueness of weak solutions for quasilinear elliptic equations in divergence form. Some counterexamples are given to show that our uniqueness result cannot be improved in the general case.
Xu Zhang
doaj +1 more source
Checkpoint blockade and the stem‐like T cell trade‐off
Molecular Oncology, EarlyView.Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Solutions for p(x)-Laplace equations with critical frequency
Electronic Journal of Differential Equations, 2018 This article concerns the p(x)-Laplace equations with critical frequency $$ -\text{div}(|\nabla u|^{p(x)-2}\nabla u)+V(x)|u|^{p(x)-2}u=f(x,u)\quad \text{in } \mathbb{R}^N, $$ where ...
Xia Zhang, Chao Zhang, Huimin Gao
doaj
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Weak solutions for quasilinear degenerate parabolic systems
Electronic Journal of Differential Equations, 2006 This paper concerns the initial Dirichlet boundary-value problem for a class of quasilinear degenerate parabolic systems. Due to the degeneracies, the problem does not have classical solutions in general.
Zheng'an Yao, Wenshu Zhou
doaj
FEBS Open Bio, EarlyView.We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
wiley +1 more source
Weak solution of the nonuniform multiconductor transmission lines [PDF]
, 1998 Canavero, Flavio, Grivet-Talocia, S.
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source