Results 91 to 100 of about 4,913,850 (297)
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
A quasistatic electro-elastic contact problem with normal compliance, friction and adhesion
Electronic Journal of Differential Equations, 2014 In this article we consider a mathematical model which describes the contact between a piezoelectric body and a deformable foundation. The constitutive law is assumed linear electro-elastic and the process is quasistatic.
Nadhir Chougui, Salah Drabla
doaj
Uniqueness of weak solution for nonlinear elliptic equations in divergence form
International Journal of Mathematics and Mathematical Sciences, 2000 We study the uniqueness of weak solutions for quasilinear elliptic equations in divergence form. Some counterexamples are given to show that our uniqueness result cannot be improved in the general case.
Xu Zhang
doaj +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
A Pretest to Differentiate Between Weak and Nearly-Weak Instrument Asymptotics [PDF]
We propose a pretest, bootstrap Kolmogorov-Smirnov test, to differentiate between weak and nearly-weak asymptotics. This is based on bootstrapping Wald Continuous Updating Estimator (CUE) based test.
Mehmet Caner
core
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
A Hardware Generator of Multi-point Distributed Random Numbers for Monte Carlo Simulation [PDF]
Monte Carlo simulation of weak approximations of stochastic differential equations constitutes an intensive computational task. In applications such as finance, for instance, to achieve "real time" execution, as often required, one needs highly efficient
Filippo Martini +3 more
core
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Solutions for p(x)-Laplace equations with critical frequency
Electronic Journal of Differential Equations, 2018 This article concerns the p(x)-Laplace equations with critical frequency $$ -\text{div}(|\nabla u|^{p(x)-2}\nabla u)+V(x)|u|^{p(x)-2}u=f(x,u)\quad \text{in } \mathbb{R}^N, $$ where ...
Xia Zhang, Chao Zhang, Huimin Gao
doaj