Results 41 to 50 of about 4,913,850 (297)
On Weak Solutions of Highly Degenerate SDEs
Automation and Remote Control, 2020 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Large-time behavior of the weak solution to 3D Navier-Stokes equations [PDF]
, 2012 The weak solution to the Navier–Stokes equations in a bounded domain D ⊂ R[superscript 3] with a smooth boundary is proved to be unique provided that it satisfies an additional requirement. This solution exists for all t ≥ 0.
Ramm, A.G., Ramm, Alexander G.
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Mathematical Modelling and Analysis, 2011 In the paper existence and uniqueness of weak solutions of boundary value problems in nontube domains for fourth-order equations of composite type are proved by methods of functional analysis.
Victor Korzyuk, Olga Kovnatskaya
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FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Electronic Journal of Differential Equations, 1998 We study the initial value problem for the 3-D Euler equation when the fluid is inviscid and incompressible, and flows with axisymmetry and without swirl.
Dongho Chae, Oleg Yu Imanuvilov
doaj
Weak Solution to KWC Systems of Pseudo-parabolic Type
Известия Иркутского государственного университета: Серия "Математика"In this paper, a class of systems of pseudo-parabolic PDEs is considered. These systems (S)ε are derived as a pseudo-parabolic dissipation system of Kobayashi– Warren–Carter energy, proposed by [Kobayashi et al., Physica D, 140, 141–150 (2000)], to ...
D. Mizuno
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