Results 61 to 70 of about 696,986 (308)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Nonuniqueness of Weak Solutions to the SQG Equation [PDF]

open access: yesCommunications on Pure and Applied Mathematics, 2019
We prove that weak solutions of the inviscid SQG equations are not unique, thereby answering Open Problem 11 of De Lellis and Székelyhidi in 2012. Moreover, we also show that weak solutions of the dissipative SQG equation are not unique, even if the fractional dissipation is stronger than the square root of the Laplacian.
Buckmaster, Tristan   +2 more
openaire   +3 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Existence of weak solutions for a non-homogeneous solidification mathematical model

open access: yesElectronic Journal of Differential Equations, 2006
This article studies the existence of weak solutions for a stationary non-homogeneous system of equations describing the solidification process of a binary alloy confined to a regular bounded domain in $R^3$ and having mixed boundary conditions.
Elva Ortega-Torres, Mario M. Duran
doaj  

On the weak solution of moving boundary problems

open access: yes, 1978
The weak formulation of moving boundary problems with possibly vanishing specific heat, that is governed by parabolic and/or elliptic differential equations, is developed. The uniqueness of the resulting weak solution is then proved.
Crowley, AB
core  

On the regularity of weak solutions to $H$-systems

open access: yesRendiconti Lincei, Matematica e Applicazioni, 2007
In this paper we prove that every weak solution to the H -surface equation is locally bounded, provided the prescribed mean curvature H satisfies a suitable ...
openaire   +5 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Existence of global solutions for reaction diffusion systems modeling the electrodeposition of alloys with initial data measures

open access: yesElectronic Journal of Differential Equations, 2017
In this work, we are interested in the mathematical model of reaction diffusion systems. The originality of our study is to work with concentrations appearing in reactors together with measure initial data.
Nour Eddine Alaa, Fatima Aqel
doaj  

Numerical verification of weak solutions of a Crocco boundary problem (typical) using an implicit second order difference scheme

open access: yesSt. Petersburg Polytechnical University Journal: Physics and Mathematics, 2019
To verify the solution of a typical Crocco boundary problem, a numerical experiment was performed using an implicit second-order difference scheme. It is shown that a numerical solution approximates a weak solution of a typical Crocco limit problem ...
Petrichenko Mikhail, Kotov Eugene
doaj   +1 more source

Uniqueness of global weak solution for some hyperbolic conservation system [PDF]

open access: yes, 2014
En el presente trabajo se estudia la unicidad de soluciones entrópicas para los problemas de Riemann y Cauchy asociados al sistema de relajación de Suliciu donde el dato inicial satisface las condiciones H1 y H2.
De la Cruz Guerrero, Richard Alexander
core  

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