Results 61 to 70 of about 5,114,170 (301)

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Existence of global solutions for reaction diffusion systems modeling the electrodeposition of alloys with initial data measures

Electronic Journal of Differential Equations, 2017
In this work, we are interested in the mathematical model of reaction diffusion systems. The originality of our study is to work with concentrations appearing in reactors together with measure initial data.
Nour Eddine Alaa, Fatima Aqel
doaj  

Nonexistence of solutions results for certain fractional differential equations

Mathematical Modelling and Analysis, 2011
This paper is meant to establish sufficient conditions for the nonexistence of weak solutions to nonlinear fractional diffusion equation in space and time with nonlinear convective term. The Fujita exponent is determined.
Mohamed Berbiche
doaj   +1 more source

A problem with dynamical boundary condition for a one-dimensional hyperbolic equation

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2020
In this paper, we consider a problem with dynamical boundary conditions for a hyperbolic equation. The dynamical boundary condition is a convenient method to take into account the presence of certain damper when fixing the end of a string or a beam ...
Aleksandr Borisovich Beylin, Ludmila Stepanovna Pulkina   +1 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Weak solutions and optimal controls of stochastic fractional reaction-diffusion systems

Open Mathematics, 2020
The aim of this paper is to investigate a class of nonlinear stochastic reaction-diffusion systems involving fractional Laplacian in a bounded domain. First, the existence and uniqueness of weak solutions are proved by using Galërkin’s method.
Fu Yongqiang, Yan Lixu
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Weak solutions for p-Laplacian equation

Advances in Nonlinear Analysis, 2012
In this work we consider the p-Laplacian type parabolic equation with Dirichlet boundary condition and establish the existence of weak solutions using Leray–Schauder's fixed point theorem and semi-discretization process.
Bhuvaneswari Venkatasubramaniam, Lingeshwaran Shangerganesh, Balachandran Krishnan   +2 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source