Results 51 to 60 of about 2,506,197 (280)

Existence and uniqueness of global weak solutions to a Cahn-Hilliard-Stokes-Darcy system for two phase incompressible flows in karstic geometry

open access: yes, 2014
We study the well-posedness of a coupled Cahn-Hilliard-Stokes-Darcy system which is a diffuse-interface model for essentially immiscible two phase incompressible flows with matched density in a karstic geometry.
Han, Daozhi, Wang, Xiaoming, WU, Hao
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Weak Solution to KWC Systems of Pseudo-parabolic Type

open access: yesИзвестия Иркутского государственного университета: Серия "Математика"
In this paper, a class of systems of pseudo-parabolic PDEs is considered. These systems (S)ε are derived as a pseudo-parabolic dissipation system of Kobayashi– Warren–Carter energy, proposed by [Kobayashi et al., Physica D, 140, 141–150 (2000)], to ...
D. Mizuno
doaj   +1 more source

Convergence in $C(\lbrack0,T\rbrack;L^2(\Omega))$ of weak solutions to perturbed doubly degenerate parabolic equations

open access: yes, 2016
We study the behaviour of solutions to a class of nonlinear degenerate parabolic problems when the data are perturbed. The class includes the Richards equation, Stefan problem and the parabolic $p$-Laplace equation.
Droniou, Jérôme   +2 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Weak solutions of boundary value problems in nontube domains for fourth-order equations of composite type

open access: yesMathematical Modelling and Analysis, 2011
In the paper existence and uniqueness of weak solutions of boundary value problems in nontube domains for fourth-order equations of composite type are proved by methods of functional analysis.
Victor Korzyuk, Olga Kovnatskaya
doaj   +1 more source

Nonuniqueness of weak solutions to the Navier-Stokes equation

open access: yes, 2018
For initial datum of finite kinetic energy, Leray has proven in 1934 that there exists at least one global in time finite energy weak solution of the 3D Navier-Stokes equations. In this paper we prove that weak solutions of the 3D Navier-Stokes equations
Buckmaster, Tristan, Vicol, Vlad
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Optimal control of a viscous generalized θ-type dispersive equation with weak dissipation

open access: yesOpen Mathematics, 2020
In this paper, we investigate the problem for optimal control of a viscous generalized θ\theta -type dispersive equation (VG θ\theta -type DE) with weak dissipation. First, we prove the existence and uniqueness of weak solution to the equation.
Fan Guobing, Yang Zhifeng
doaj   +1 more source

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