Results 111 to 120 of about 634,419 (341)
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He+5 more
wiley +1 more source
2D Stochastic Chemotaxis-Navier-Stokes System [PDF]
In this paper, we establish the existence and uniqueness of both mild(/variational) solutions and weak (in the sense of PDE) solutions of coupled system of 2D stochastic Chemotaxis-Navier-Stokes equations. The mild/variational solution is obtained through a fixed point argument in a purposely constructed Banach space.
arxiv
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy+14 more
wiley +1 more source
On viscosity and weak solutions for non-homogeneous p-Laplace equations
In this manuscript, we study the relation between viscosity and weak solutions for non-homogeneous p-Laplace equations with lower-order term depending on x, u and ∇u{\nabla u}.
Medina Maria, Ochoa Pablo
doaj +1 more source
III. On weak electrolytes and towards a dynamical theory of solutions [PDF]
William Sutherland
openalex +1 more source
GPR142, a tryptophan‐sensing receptor, stimulates gastrointestinal hormones like ghrelin and is linked to inflammation regulation. Proinflammatory cytokines suppress ghrelin production, while tryptophan levels decrease via IDO1 activation. Our findings reveal that proinflammatory cytokines directly regulate GPR142 expression in ghrelin‐producing cells,
Yoko Ueda+15 more
wiley +1 more source
Weak Random Periodic Solutions of Random Dynamical Systems [PDF]
We first introduce the concept of weak random periodic solutions of random dynamical systems. Then, we discuss the existence of such periodic solutions. Further, we introduce the definition of weak random periodic measures and study their relationship with weak random periodic solutions.
arxiv
Periodic solutions of the first boundary value problem for a linear and weakly nonlinear heat equation [PDF]
Věnceslava Šťastnová, Otto Vejvoda
openalex +1 more source
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law+6 more
wiley +1 more source
Existence Theorems for Weak and Usual Optimal Solutions in Lagrange Problems with Unilateral Constraints. II. Existence Theorems for Weak Solutions [PDF]
Lamberto Cesari
openalex +1 more source