Results 101 to 110 of about 4,087,279 (255)
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Regularity of weak solutions to certain degenerate elliptic equations [PDF]
, 2006 summary:In this article we establish the existence of higher order weak derivatives of weak solutions of Dirichlet problem for a class of degenerate elliptic ...
Cavalheiro, Albo Carlos
core
Weak solutions to lubrication systems describing the evolution of bilayer thin films
, 2014 The existence of global non-negative weak solutions is proved for coupled onedimensional lubrication systems that describe the evolution of nanoscopic bilayer thin polymer films that take account of Navier-slip or no-slip conditions at both liquid-liquid
Jachalski, Sebastian +2 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Global existence and regularity of solutions for active liquid crystals [PDF]
, 2017 We study the hydrodynamics of active liquid crystals in the Beris-Edwards hydrodynamic framework with the Landau-de Gennes Q-tensor order parameter to describe liquid crystalline ordering.
Chen, Gui-Qiang +3 more
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
A nonlinear wave equation with a nonlinear integral equation involving the boundary value
Electronic Journal of Differential Equations, 2004 We consider the initial-boundary value problem for the nonlinear wave equation $$displaylines{ u_{tt}-u_{xx}+f(u,u_{t})=0,quad xin Omega =(0,1 ...
Thanh Long Nguyen, Tien Dung Bui
doaj
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source